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PEG-50 LANOLIN.

Valuable CAS 61790-81-6 / SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

PEG-50 Lanolin is a versatile polyethylene glycol derivative of lanolin, primarily recognized for its emulsifying and conditioning properties. It aids in stabilizing complex formulations while simultaneously enhancing skin hydration and softness through its emollient action.

Summary

Emulsifying Skin Conditioning Emollient Surfactant - Cleansing Solubilizer Hair Conditioning

Science

Mechanism of Action

This ingredient functions by reducing surface tension, enabling the stable emulsification of oil and water phases within a formulation. On the skin, it acts as an emollient, lubricating the surface to impart a smooth texture and forming a barrier that minimizes transepidermal water loss, thus maintaining skin hydration. Furthermore, it serves as a solubilizer, facilitating the incorporation of poorly soluble compounds into aqueous systems, and offers a mild cleansing effect by breaking down oils and impurities.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Clinical reviews indicate that PEG Lanolin ingredients, including PEG-50 Lanolin, demonstrated negligible to mild skin irritation and were nonsensitizing in animal studies at concentrations ranging from 10% to 100%.
  2. 02 In human patch tests, PEG-50 Lanolin was reported to be nonirritating and nonsensitizing at concentrations up to 60%.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 2 – 10
0 7 14

Stability

PEG-50 Lanolin exhibits excellent stability across a broad pH spectrum, from 2 to 10. It shows only minor susceptibility to oxidative and reducing agents. As a polyethylene glycol derivative, it is generally well-tolerated by microbial action, often negating the need for extensive additional preservation.

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The CIR Expert Panel has deemed PEG Lanolin ingredients, including PEG-50 Lanolin, safe for use in cosmetic and personal care products. Safety assessments confirm its non-irritating and non-sensitizing profile at concentrations up to 60% in human subjects and 100% in animal models. Trace amounts of 1,4-dioxane, an ethoxylation byproduct, may be present but are rigorously controlled through standard purification processes.

Your Skin

Skin Compatibility

No Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

PEG-50 Lanolin is a valuable multifunctional ingredient, offering robust emulsification, skin conditioning, and solubilizing capabilities with a strong safety profile and broad formulation compatibility.

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References

Sources