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PEG-40 LANOLIN.

Valuable CAS 61790-81-6 / SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

PEG-40 Lanolin is an ethoxylated derivative of lanolin, serving as a multifunctional ingredient in skincare formulations. It excels as an emulsifier, solubilizer, and emollient, promoting enhanced skin hydration and a smoother texture. This versatile ingredient aids in integrating oil-soluble compounds into water-based systems and is generally well-tolerated.

Summary

Emulsifier Solubilizer Emollient Surfactant Lubricant Moisturizer

Science

Mechanism of Action

PEG-40 Lanolin functions primarily as an emulsifier, solubilizer, and emollient. It effectively reduces the surface tension between immiscible oil and water phases, thereby stabilizing emulsions. On the skin's surface, it acts as a lubricant, contributing to a soft and smooth appearance. As an emollient, it conditions the skin, minimizes transepidermal water loss, and boosts hydration, mirroring the benefits of natural lanolin. Its ethoxylated nature renders it water-soluble, facilitating the incorporation of oil-soluble ingredients into aqueous formulations.

Research

Clinical Evidence

Medium confidence
Effective range 1–5%
Optimal

1-5%

Key findings

  1. 01 Recommended use levels of 1-5% in formulations provide effective moisturizing, lubricating, and emollient properties, alongside aiding in the solubilization of oils and perfumes.

Transparency

Dusting Analysis

Not commonly dusted

PEG-40 Lanolin is predominantly a functional ingredient crucial for formulation stability and skin conditioning, rather than a 'hero' active ingredient that is commonly over-promoted.

The Formula

Formulation

Solubility
Water
Optimal pH 2 – 10
0 7 14

Stability

This ingredient exhibits broad stability across a pH range of 2 to 10. It demonstrates compatibility with a majority of other solubilizers, including up to 10% electrolyte solutions, and shows only slight susceptibility to oxidative and reducing agents. To maintain integrity, prolonged heating above 80°C should be avoided during processing.

Synergies

  • Most solubilizers
  • Up to 10% electrolyte solutions

Safety

Safety Profile

CIR Status
Safe as used
Max tested
60%
Sensitization risk Low

The CIR Expert Panel has concluded that PEG-40 Lanolin is safe for cosmetic use. Clinical studies, including human patch tests up to 60% concentration, have shown it to be nonirritating and nonsensitizing. While concerns exist regarding potential 1,4-dioxane contamination, a by-product of ethoxylation, this can be effectively mitigated through appropriate purification steps. It is important to distinguish from natural lanolin, which can occasionally act as a weak sensitizer on compromised skin; PEG-40 Lanolin has been reported as nonsensitizing in relevant studies.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Medium

Our Assessment

Verdict

Valuable

PEG-40 Lanolin is a valuable multifunctional ingredient offering excellent emulsifying and solubilizing properties, alongside effective emollience and hydration for dry and normal skin types with a low risk of irritation.

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