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Moumoujus

PEG-40 HYDROGENATED LANOLIN.

Valuable CAS 68648-27-1 / HAIR CONDITIONING, SURFACTANT - EMULSIFYING

This PEG-derived ingredient functions as a versatile emollient and emulsifier, enhancing skin softness, promoting hydration, and stabilizing oil-in-water formulations. It contributes to a smooth skin feel while efficiently blending immiscible ingredients.

Summary

Emollient Emulsifying Agent Surfactant Hair Conditioning Agent Humectant Solubilizer Consistency Enhancer

Science

Mechanism of Action

PEG-40 Hydrogenated Lanolin operates by reducing surface tension, which facilitates the formation and stability of emulsions by uniformly dispersing oil and water components. On the skin, it acts as a lubricant, imparting a smooth and soft texture. Its polyethylene glycol structure also enables it to form hydrogen bonds with water molecules, thereby retaining moisture, providing long-term hydration, and minimizing transepidermal water loss.

Research

Clinical Evidence

High confidence
Effective range 0.001–15%
Optimal

15%

Key findings

  1. 01 CIR Safety Review found the ingredient to be nonirritating and nonsensitizing in patient studies at concentrations ranging from 10% to 60%.
  2. 02 Further CIR evaluations demonstrated mild or negligible skin irritation and no sensitizing effects at concentrations up to 100%.

Transparency

Dusting Analysis

Not commonly dusted

PEG-40 Hydrogenated Lanolin serves distinct functional roles in formulations, including emulsification, emolliency, and humectancy, making its inclusion purposeful rather than for 'dusting'.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Exhibits robust stability, tolerating a broad pH spectrum from acidic to alkaline conditions. It is not microbiologically sensitive, often reducing the need for extensive preservation systems in formulations.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
15%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has deemed PEG-40 Hydrogenated Lanolin safe for cosmetic application, consistent with concentrations up to 15%. Acute oral, dermal, and inhalation toxicity studies demonstrated non-toxic outcomes. Clinical data indicates a low risk of irritation or sensitization, with studies showing non-irritating effects in patients at 10-60% and only mild or negligible irritation up to 100%. Formulators are advised to ensure purification steps minimize residual 1,4-dioxane, a potential by-product of ethoxylation, to maintain safety standards.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

PEG-40 Hydrogenated Lanolin is a valuable multi-functional ingredient that enhances skin hydration and softness while contributing significantly to the stability and texture of cosmetic formulations.

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