Science
Mechanism of Action
This ingredient primarily functions as an emulsifying agent by significantly lowering the surface tension between immiscible phases, thereby creating and stabilizing oil-in-water emulsions. As a nonionic surfactant, it aids in gentle cleansing and acts as a solubilizer, enabling the dispersion of hydrophobic compounds within aqueous formulations. Furthermore, its polyethylene glycol derivative structure allows it to attract and retain water through hydrogen bonding, promoting skin hydration and mitigating transepidermal water loss. It also modulates product rheology, imparts a smooth after-feel, and can reduce irritation when co-formulated with anionic surfactants, while potentially enhancing the dermal absorption of other actives.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
PEG-35 Soy Glycerides is a nonionic ingredient, ensuring broad compatibility with various ionic species in formulations. It integrates effectively into clear aqueous systems and performs optimally as an emulsifying agent with a hydrophilic-lipophilic balance (HLB) value ranging from 16 to 18.
Synergies
- Acts as an irritation-reducing agent when used as a secondary surfactant in anionic systems.
- Enhances the penetration of other active ingredients into the skin, optimizing their delivery.
Conflicts
- Formulators must exercise caution when combining with ingredients whose safety assessments rely on minimal dermal absorption, due to its penetration-enhancing properties.
- Trace amounts of 1,4-dioxane, a potential byproduct of the ethoxylation process, may be present and require strict control through purification steps.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that PEGylated alkyl glycerides, including PEG-35 Soy Glycerides, are safe for use in current practices and concentrations when formulated to be non-irritating. This assessment supersedes earlier limitations for related ingredients. Formulators are advised to account for its ability to enhance the dermal penetration of other ingredients, particularly those whose safety profiles are based on limited absorption. Manufacturers are also cautioned to ensure purification steps adequately control any residual 1,4-dioxane.
Your Skin
Skin Compatibility
Our Assessment
Verdict
PEG-35 Soy Glycerides is a valuable multi-functional ingredient, effectively stabilizing emulsions, enhancing hydration, and offering formulation versatility, provided formulators carefully consider its penetration-enhancing properties.
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References
Sources