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PEG-27 LANOLIN.

Valuable CAS 61790-81-6 / SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

PEG-27 Lanolin is a water-soluble polyether derivative of lanolin, primarily recognized for its skin-conditioning, emulsifying, and solubilizing properties. It enhances skin suppleness and smoothness while stabilizing formulations and mitigating the drying effects of cleansing agents.

Summary

emulsifying surfactant skin conditioning solubilizer humectant consistency enhancer binding agent

Science

Mechanism of Action

On the skin's surface, PEG-27 Lanolin functions as a lubricant, contributing to a soft and smooth appearance. As an emulsifier, it effectively reduces surface tension between oil and water phases, aiding in the formation and stability of emulsions. Additionally, it acts as a solubilizer for various cosmetic ingredients and helps minimize the defatting action of detergents on both skin and hair.

Research

Clinical Evidence

High confidence
Effective range 10–60%
Optimal

Concentrations between 10% and 60% are clinically reported to be nonirritating and nonsensitizing, offering optimal beneficial effects without adverse reactions.

Key findings

  1. 01 Clinical assessments by the CIR Safety Review reported PEG-27 Lanolin as nonirritating and nonsensitizing in patients at concentrations ranging from 10% to 60%.
  2. 02 Even at higher concentrations, from 10% up to 100%, it caused only mild or negligible skin irritation, and concentrations between 50% and 100% resulted in little or no eye irritation.

Transparency

Dusting Analysis

Commonly dusted
Min. effective
4%
Red flag below
4%

When incorporated into products that may become airborne (up to 4% concentration) or aerosolized (up to 2%), data indicate PEG-27 Lanolin has minimal potential for respiratory effects and is not anticipated to cause direct toxic effects in the upper respiratory tract.

The Formula

Formulation

Solubility
Water
Optimal pH 2 – 10
0 7 14

Stability

PEG-27 Lanolin exhibits excellent stability across a wide pH range of 2 to 10. As a nonionic derivative, it is compatible with most other solubilizers, including electrolyte solutions up to 10%, and demonstrates slight resistance to oxidative and reducing agents.

Synergies

  • Compatible with most other solubilizers
  • Compatible with up to 10% electrolyte solutions

Safety

Safety Profile

CIR Status
Safe as used
Max tested
4%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel concluded that polyether lanolins, including PEG-27 Lanolin, are safe as used in cosmetics. This conclusion was re-affirmed in 2003, with a reassessment re-opened in June 2023. While trace amounts of 1,4-dioxane, a by-product of ethoxylation, may be present, these can be controlled through purification. Despite lanolin being designated the 2023 Allergen of the Year, the CIR specifically found polyether lanolins to be safe and distinct from raw lanolin or lanolin alcohol regarding sensitization risk.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

PEG-27 Lanolin is a valuable, multifunctional ingredient that enhances skin hydration and smoothness while effectively stabilizing formulations, presenting a low irritation and sensitization risk.

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