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Moumoujus

PEG-25 PHYTOSTANOL.

Valuable CAS - / SURFACTANT - EMULSIFYING

PEG-25 PHYTOSTANOL is a versatile nonionic surfactant and emulsifier, adept at stabilizing oil-in-water emulsions. Beyond its formulation utility, it actively conditions skin by enhancing moisture retention and supporting vital collagen and elastin production.

Summary

Emulsifying Skin conditioning Humectant Antioxidant

Science

Mechanism of Action

This ingredient operates through a dual mechanism. Its polyethylene glycol (PEG) component is hydrophilic, forming hydrogen bonds with water molecules to significantly increase moisture retention and reduce transepidermal water loss, thereby promoting sustained hydration. Concurrently, the phytostanol component, similar to phytosterols, is believed to stimulate fibroblast growth factor activity, which enhances the secretion of collagen and elastin for improved skin elasticity and firmness, while also offering moisturizing and antioxidant benefits.

Research

Clinical Evidence

Medium confidence
Effective range ≤2%
Optimal

2%

Key findings

  1. 01 A safety assessment of PEG-5 Soy Sterol, a structurally similar compound, demonstrated no dermal or ocular irritation, sensitization, or photosensitization at concentrations up to 2%.
  2. 02 Separately, PEG-25 Propylene Glycol Stearate, another related ingredient, was found safe in cosmetic applications at concentrations not exceeding 10% and yielded negative results in clinical patch tests.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Aqueous solutions of general PEGs, including PEG-25 PHYTOSTANOL, exhibit stability at room temperature without bond hydrolysis. However, exposure to elevated temperatures, oxygen, or the absence of antioxidants can lead to degradation and a decrease in pH. It demonstrates superior stability against heat and oxidation compared to soy lecithin and can facilitate the creation of glossy, low-viscosity emulsions.

Conflicts

  • Phenol
  • Sorbitol
  • Tannic acid
  • Salicylic acid
  • May compromise the integrity of certain plastics
  • May diminish the efficacy of other antimicrobial preservatives

Safety

Safety Profile

CIR Status
Safe with restrictions
Max tested
2%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel deemed PEGs Soy Sterol, a group encompassing closely related PEG-25 Soy Sterol, safe for cosmetic use under specific conditions. A maximum use concentration of 2% is advised for leave-on products. It is critically important to avoid use on compromised or damaged skin, as evidence suggests potential sensitization and nephrotoxicity when PEG-based antimicrobial preparations were applied to burn patients. Manufacturers are also mandated to ensure impurities such as ethylene oxide (maximum 1 ppm) and 1,4-dioxane (maximum 5 ppm) are effectively removed.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

PEG-25 PHYTOSTANOL is a valuable multifunctional ingredient, offering both superior emulsification and significant skin conditioning benefits, including hydration and support for collagen production, while maintaining a low irritancy profile on intact skin.

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