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PEG-24 LANOLIN.

Valuable CAS 61790-81-6 / SURFACTANT - EMULSIFYING

PEG-24 Lanolin is a polyoxyethylene derivative of lanolin that functions primarily as an emulsifier and skin conditioning agent. It facilitates the stable blending of oil and water phases while imparting emollient and moisturizing benefits for a soft, smooth skin feel.

Summary

Emulsifying Surfactant Hair Conditioning Skin Conditioning - Emollient

Science

Mechanism of Action

This ingredient reduces surface tension between immiscible substances, enabling the formation of stable emulsions. On the skin, PEG-24 Lanolin acts as a lubricant and forms a subtle occlusive layer, which effectively prevents excessive transepidermal water loss, contributing to enhanced hydration, smoothness, and softness of the epidermis.

Research

Clinical Evidence

High confidence
Effective range 10–60%
Optimal

N/A

Key findings

  1. 01 Human patient studies demonstrated PEG-24 Lanolin concentrations between 10% and 60% to be non-irritating and non-sensitizing.
  2. 02 Animal studies (rabbits) showed mild or negligible skin irritation and no ocular irritation at concentrations up to 100%.

Transparency

Dusting Analysis

Not commonly dusted

PEG-24 Lanolin serves established functional roles as an emulsifier and skin conditioner, and is not typically subject to exaggerated marketing claims beyond its technical capabilities.

The Formula

Formulation

Solubility
Both
Optimal pH 2 – 10
0 7 14

Stability

The ingredient is stable across a broad pH range of 2 to 10 and exhibits minimal degradation from oxidative or reducing agents. For optimal stability, prolonged heating above 80 °C should be avoided.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
60%
Sensitization risk Moderate

The CIR Expert Panel concluded PEG-24 Lanolin is safe for cosmetic use, reaffirmed in reviews up to March 2024. While studies show it is non-sensitizing at concentrations up to 60%, the base ingredient lanolin was designated the 2023 Allergen of the Year, warranting caution for individuals with known lanolin sensitivities. Trace amounts of 1,4-dioxane, a by-product of ethoxylation, can be controlled through purification. Lanolin holds FDA status as a permitted food additive and an active ingredient in some OTC drugs.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Medium

Our Assessment

Verdict

Valuable

PEG-24 Lanolin is a valuable, multifunctional ingredient for formulations, offering effective emulsification and skin conditioning with a generally strong safety profile, though potential for sensitization exists in individuals with pre-existing lanolin allergies.

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