Science
Mechanism of Action
PEG-180 operates as a humectant, actively attracting and binding water molecules to the skin's surface, which helps maintain hydration and promotes a soft, supple feel. Due to its substantial molecular size, it largely remains on the skin's exterior, avoiding systemic absorption. In formulations, it enhances ingredient distribution by dissolving oil-soluble components into water-based systems, stabilizes emulsions by blending oil and water phases, and optimizes product consistency and texture.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 Polyethylene glycols, including PEG-180, have consistently demonstrated minimal skin irritation and no significant sensitization in human clinical trials at concentrations up to 25%.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
PEG-180 is a stable ingredient, inherently resistant to microbiological growth, often negating the need for additional preservatives. As a solid PEG, it effectively enhances product consistency and offers humectant benefits. Its water solubility and hygroscopicity tend to decrease with increasing molar mass, but it remains well tolerated within formulations.
Conflicts
- strong oxidizing agents
Safety
Safety Profile
The CIR Expert Panel has affirmed the safety of PEG-180 for cosmetic use. Its high molecular weight prevents absorption through intact skin, mitigating systemic toxicity concerns. While kidney toxicity was noted in severely burned patients treated with a PEG-based antimicrobial cream, this was not observed in studies involving intact skin. The FDA has also recognized PEG-180 positively for indirect food additive applications.
Your Skin
Skin Compatibility
Our Assessment
Verdict
PEG-180 is a valuable multi-functional ingredient, providing effective hydration and excellent formulation stability with a robust safety profile and minimal irritation potential across all skin types.
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