Science
Mechanism of Action
On the skin, PEG-175 DIISOSTEARATE functions as an effective humectant, forming hydrogen bonds with water molecules to draw and retain moisture, thereby supporting long-term skin hydration and potentially reducing transepidermal water loss. Within a formulation, its surfactant properties enable the creation of stable emulsions by reducing interfacial tension between immiscible phases, while its viscosity-controlling capabilities optimize product consistency and flow.
Research
Clinical Evidence
Medium confidence25%
Key findings
- 01 Safety Assessment of PEG Diesters as Used in Cosmetics - CIR Report Data Sheet (assessed as part of broader PEG Stearates group)
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Possessing a high number of ethylene oxide units (n=175), PEG-175 DIISOSTEARATE exhibits strong water solubility, which increases proportionally with longer PEG chains. It serves effectively as a viscosity builder in water-dominant systems such as shampoos and shower gels. Formulation protocols must ensure the final product is non-irritating, and considerations for potential trace amounts of ethylene oxide impurities are prudent.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel concluded that PEG diesters, including PEG-175 DIISOSTEARATE, are safe for use in cosmetics when formulated to be non-irritating. While no specific maximum concentration was established for PEG-175 DIISOSTEARATE itself, related PEG dilaurates and PEG stearates were deemed safe at concentrations up to 25%. It is noteworthy that an industry survey indicated a similar ingredient, PEG-175 distearate, is used at much lower concentrations, for example, up to 0.089% in shaving creams. Isolated instances of sensitization and nephrotoxicity have been observed in burn patients treated with PEG-based creams, indicating a potential risk only on severely compromised or damaged skin, not intact skin.
Your Skin
Skin Compatibility
Our Assessment
Verdict
PEG-175 DIISOSTEARATE is a valuable polyfunctional ingredient, effectively stabilizing emulsions, modulating viscosity, and offering humectant properties, deemed compatible with all skin types when precisely formulated to be non-irritating.
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References
Sources