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PEG-12 LANOLATE.

Valuable CAS 68459-50-7 / SURFACTANT - EMULSIFYING

PEG-12 Lanolate is a multi-functional ingredient acting as a surfactant, emulsifier, and humectant. It effectively conditions the skin, aids in hydration by attracting water, and contributes to forming a protective barrier, making it suitable for a broad spectrum of skincare and cosmetic applications.

Summary

Emulsifying Surfactant Skin Conditioning Emollient Humectant

Science

Mechanism of Action

This polyether lanolin derivative primarily functions as an effective surfactant and emulsifying agent, crucial for stabilizing oil-in-water or water-in-oil formulations. As a skin conditioning agent and emollient, it imparts a smooth, softened feel to the skin. Additionally, its polyethylene glycol (PEG) component provides humectant capabilities, actively drawing moisture into the stratum corneum and potentially minimizing transepidermal water loss by forming a lightweight occlusive layer.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

While specific pH stability data for PEG-12 Lanolate is not explicitly provided, related PEG derivatives, such as PEG-8 Dimethicone, demonstrate stability within a pH range of 5.5 to 8.5.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
60%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has affirmed polyether lanolins, including PEG lanolins, as safe for use in cosmetic applications up to 60% concentration. Comprehensive acute oral, dermal, and inhalation studies confirmed their non-toxic nature, with minimal to no ocular irritation observed in rabbits even at 100% concentration. Furthermore, animal and human assays demonstrated no significant irritation or sensitization potential. The previous advisory regarding the application of PEGs on compromised skin has been re-evaluated and removed by the CIR Expert Panel. PEG ingredients are recognized as Generally Recognized As Safe (GRAS) by the FDA, with maximum usage levels specified in the Inactive Ingredient Guide. Manufacturers are advised to control potential trace amounts of 1,4-dioxane, an ethoxylation by-product, through standard purification processes.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

PEG-12 Lanolate is a valuable multi-functional ingredient that enhances formulation stability, provides skin conditioning benefits, and improves hydration across all skin types, supported by a strong safety profile.

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