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Moumoujus

PASSIFLORA QUADRANGULARIS HULL EXTRACT.

Insufficient Data / SKIN CONDITIONING

Passiflora Quadrangularis Hull Extract, derived from the Giant Granadilla, holds potential for diverse skin benefits. While direct clinical data specific to the hull extract is limited, related Passiflora quadrangularis fruit extracts have demonstrated promise in enhancing skin hydration, mitigating the appearance of wrinkles, and offering skin brightening effects.

Summary

Antioxidant Anti-aging Skin conditioning Skin brightening Hydrating

Science

Mechanism of Action

The proposed mechanism of action, largely observed with Passiflora quadrangularis fruit extracts, involves a multi-pronged approach to skin health. These extracts exhibit anti-collagenase, anti-elastase, and anti-hyaluronidase activities, supporting the maintenance of skin elasticity and hydration, thereby contributing to anti-aging effects. They also possess significant antioxidant properties, effectively scavenging DPPH and ABTS free radicals. Furthermore, these extracts can contribute to skin whitening by inhibiting the tyrosinase enzyme, which reduces melanin production. These beneficial attributes are attributed to the rich presence of phenolic and flavonoid compounds.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

No specific data regarding dusting practices or thresholds for this particular extract was identified in the research.

The Formula

Formulation

Solubility
Oil
Optimal pH 4 – 6
0 7 14

Stability

Challenges in formulating with Passiflora quadrangularis extracts include inherently low water solubility, potential for poor skin permeability, sensitivity to environmental factors, and an often unpleasant smell. Nanoemulsions have emerged as a viable delivery system to overcome these issues, enhancing skin permeation, stability, and potentially reducing toxicity. Formulations containing these extracts exhibit good stability within the typical skincare pH range of 4 to 6, with optimal stability noted around pH 5. They also demonstrate robust stability when exposed to varying temperatures (4 °C and 45 °C) and under controlled light conditions (30 ± 2 °C with and without direct light exposure).

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

There is currently no formal safety review status from major regulatory bodies such as CIR, SCCS, or FDA for Passiflora quadrangularis hull extract. However, a nano-serum containing P. quadrangularis fruit extracts demonstrated a very low Primary Irritation Index (PII) score of 0.2, indicating it was non-irritating and safe for human skin under test conditions.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While Passiflora quadrangularis fruit extracts exhibit promising dermatological benefits for hydration, anti-aging, and brightening, comprehensive clinical data specifically for the hull extract are presently insufficient to provide a definitive assessment of its efficacy and optimal application in precision skincare.

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