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Moumoujus

PASSIFLORA ALATA CALLUS EXTRACT.

Insufficient Data / ANTIOXIDANT, HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

Passiflora Alata Callus Extract is a botanical active celebrated for its potent anti-inflammatory and antioxidant properties, derived from the callus culture of the ornamental passionflower. It precisely targets skin discomfort by mitigating pro-inflammatory pathways, promoting a more resilient and soothed complexion.

Summary

Antioxidant Humectant Skin Conditioning Skin Protecting Anti-inflammatory Soothing

Science

Mechanism of Action

This extract functions as a multifaceted skin protectant, antioxidant, and humectant. Its primary mode of action involves inhibiting the secretion of pro-inflammatory cytokines, notably reducing IL-6 by up to 90% and IL-8 by up to 88% in human fibroblasts, including those stimulated by UVB radiation. It also contributes to reduced ICAM-1 expression. These effects are attributed to its rich profile of active compounds, including C-glycosylated flavonoids (such as orientin, vitexin, and isovitexin) and flavones (like luteolin), which collectively provide significant protective and calming benefits to the skin.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

As a specialized callus extract with identified active compounds and demonstrated specific biological activities in vitro, this ingredient appears to be a developed botanical active. However, the current absence of extensive independent clinical and safety data limits its overall validation in broad cosmetic applications.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Extraction processes typically involve water and hydroalcoholic solutions, suggesting good stability in aqueous formulations.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Unknown

Comprehensive safety evaluations (CIR, SCCS, FDA status) specifically for Passiflora Alata Callus Extract are currently not readily available. While general Passiflora alata extracts have been studied, some oral animal studies on leaf extracts have indicated potential genotoxic effects at specific doses. This highlights the necessity for further dedicated human safety assessments for topical application of this specific callus extract.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

Passiflora Alata Callus Extract demonstrates strong anti-inflammatory and antioxidant capabilities in controlled in vitro environments, suggesting a valuable role in soothing and protecting the skin; however, a definitive recommendation awaits more thorough human safety and in vivo efficacy studies.

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