Science
Mechanism of Action
This extract exerts its effects through a multi-faceted approach: it exhibits lipolytic activity by increasing free fatty acid release and modifying adipocyte morphology, leading to a higher proportion of smaller adipocytes. Concurrently, it reduces glycero-3-phosphate dehydrogenase (G3PDH) activity, an enzyme critical for intracellular lipid synthesis, thereby hindering lipogenesis. Furthermore, it boosts skin radiance by detoxifying and oxygenating cells, stimulating regeneration, and offering antioxidant protection, while its oil form contributes calming and soothing benefits.
Research
Clinical Evidence
Medium confidence0.1%
Key findings
- 01 An emulsion containing 0.1% Papaver rhoeas extract (from seeds), applied to the thighs of 22 volunteers over eight weeks, yielded statistically significant improvements in skin viscoelasticity, smoothness parameters, and blood microcirculation. It also linearized the dermo-hypodermal junction and reduced parameters associated with cellulite, such as skin blood microflow and junction length, with visible clinical improvements on digital images. These positive outcomes were found to translate to facial areas, effectively addressing dark under-eye circles, puffiness, and age-related sagging skin.
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
When applied externally in low doses, Papaver rhoeas seed extract is generally not expected to cause adverse side effects. It is important to note that the alkaloid rhoeadin, found in the white milky sap of the plant, is considered mildly toxic if consumed in excessive amounts, but this concern does not apply to its topical cosmetic use.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Papaver rhoeas seed extract is a valuable active ingredient for comprehensive skin rejuvenation, effectively addressing concerns like firmness, elasticity, and visible signs of aging and cellulite.
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References
Sources