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PAPAVER RHOEAS CALLUS EXTRACT.

Valuable CAS 84696-43-5 / ANTIOXIDANT

Papaver Rhoeas Callus Extract, derived from the red poppy, is a potent botanical active scientifically demonstrated to address multiple signs of skin aging and improve overall skin quality. It offers comprehensive benefits, from enhancing skin density and elasticity to reducing localized fat deposits and improving microcirculation, for a visibly revitalized complexion.

Anti-aging Skin firming Cellulite reduction Under-eye treatment (dark circles, puffiness) Microcirculation enhancement Hydration Antioxidant Nourishing Regenerative Lipolytic

Science

This extract operates through several biological pathways to optimize skin health. It actively reduces glycero-3-phosphate dehydrogenase (G3PDH) activity, an enzyme critical for intracellular lipid synthesis, thereby inhibiting lipogenesis. Concurrently, it stimulates lipolysis by facilitating the release of free fatty acids and modifying adipocyte structure. The extract also significantly boosts hyaluronic acid (HA) expression, increasing it by 19% in the epidermis and 33% in the papillary dermis, which promotes dermal densification and fortifies the dermal-epidermal junction. Furthermore, it enhances skin microcirculation, fosters cellular growth and macromolecule transport for restorative effects, and provides antioxidant protection via polyphenols and flavonoids.


Research

High confidence
Effective range 0.1–0.1%
Optimal

0.1%

Key findings

  1. 01 An emulsion containing 0.1% Papaver Rhoeas extract, applied over eight weeks to the thighs of 22 volunteers, yielded statistically significant improvements in skin viscoelasticity, smoothness, blood microcirculation, and linearization of the dermo-hypodermal junction, alongside a measurable reduction in cellulite. Facial application also demonstrated improved skin density, elasticity, firmness, and a reduction in both dark circles and under-eye bags.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 4.6 – 6.6
0 7 14

Stability

Aqueous extracts are preferably obtained and stored within an acidic pH range of 4.6-6.6 (average 5) for optimal stability. The extract can be preserved with authorized agents such as sodium benzoate and potassium sorbate.


Safety

CIR Status
Not reviewed
Sensitization risk Low

While Papaver Rhoeas Callus Extract has not been specifically evaluated by CIR or SCCS, related forms like Papaver Rhoeas Petal Extract are generally described as very well tolerated. These extracts typically exhibit no phototoxicity and no systemic effects from prolonged topical application, often carrying 'Non-Irritant' claims, suggesting a low risk profile for this variant as well.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Papaver Rhoeas Callus Extract is a valuable multi-functional ingredient offering significant, scientifically-backed improvements in skin structure, firmness, hydration, and microcirculation, making it highly beneficial for comprehensive anti-aging and body contouring formulations.


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