Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

PANDANUS ODORATISSIMUS SEED EXTRACT.

Insufficient Data / ANTIOXIDANT

PANDANUS ODORATISSIMUS SEED EXTRACT is a botanical ingredient derived from the seeds of the Screw Pine. Research suggests its potential as a potent antioxidant, helping to mitigate oxidative stress, and may offer anti-inflammatory and antimicrobial benefits for the skin.

Summary

Antioxidant Anti-inflammatory Antimicrobial

Science

Mechanism of Action

This seed extract functions primarily as an antioxidant by actively neutralizing free radicals, thereby reducing cellular damage and oxidative stress. Its anti-inflammatory capabilities are hypothesized to involve the modulation of key inflammatory mediators such as histamine, serotonin, and prostaglandins. Additionally, the extract exhibits antimicrobial properties, potentially by disrupting microbial cell membranes or inhibiting crucial enzymatic activities, offering broad-spectrum protection against various pathogens.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 An in vitro assessment demonstrated an IC50 value of 31.25 µg/mL, classifying Pandanus odoratissimus extract as a powerful antioxidant capable of scavenging 50% of free radicals.
  2. 02 A methanolic extract of Pandanus odoratissimus (not specifically seed extract) administered orally to rats showed significant anti-inflammatory effects, inhibiting carrageenan-induced acute paw edema by 68% and formalin-induced chronic paw edema by 64.2% at a dose of 100 mg/kg.
  3. 03 Oral administration of Pandanus odoratissimus seed extract (methanol extract) in rats demonstrated hepatoprotective effects by reducing hepatic enzyme and protein markers following paracetamol-induced damage.

Transparency

Dusting Analysis

Not commonly dusted

There is currently insufficient data to determine if PANDANUS ODORATISSIMUS SEED EXTRACT is commonly 'dusted' or used at ineffective percentages in cosmetic formulations. Its efficacy for topical application has not yet been established through human clinical trials.

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Specific optimal pH ranges for stability in cosmetic formulations have not been identified. However, studies frequently utilize methanol extracts, indicating solubility in polar solvents. As a seed extract, it is inherently complex, containing both water-soluble and oil-soluble compounds, thus its precise solubility profile will be dependent on the specific extraction methodology employed and the resultant component isolation.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

No specific safety status or maximum concentration has been established by regulatory bodies such as CIR, SCCS, or FDA for PANDANUS ODORATISSIMUS SEED EXTRACT in cosmetic applications. While oral LD50 data in rats suggests low acute oral toxicity (>2000 mg/kg), this does not provide information regarding topical safety, potential for sensitization, or irritation in humans.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

PANDANUS ODORATISSIMUS SEED EXTRACT shows promising antioxidant, anti-inflammatory, and antimicrobial properties in preliminary in vitro and animal studies, but human topical clinical data is currently insufficient to determine its precise efficacy and optimal use in skincare.

Related

Similar Ingredients

Finding similar ingredients…