Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle

PANAX QUINQUEFOLIUS EXTRACT.

Valuable / ANTIOXIDANT, SKIN CONDITIONING

Panax quinquefolius Extract, derived from American Ginseng, is a potent botanical rich in ginsenosides. This ingredient offers comprehensive skin benefits, including robust antioxidant defense, protection against environmental stressors, and improvement of overall skin health and tone.

Skin-conditioning Agent Humectant Emollient Astringent Antioxidant Anti-inflammatory Skin Brightening Anti-aging Collagen Support Skin Barrier Support Photoprotection Antimicrobial Hydration Booster

Science

Acting as a sophisticated skin-conditioning agent, Panax quinquefolius extract integrates humectant, emollient, and astringent properties to refine the complexion. Its primary mechanism involves ginsenosides, which actively shield skin cells from UVB-induced photodamage and mitigate discoloration. The extract provides robust antioxidant defense, promoting enhanced skin nutrition and metabolism through improved microcirculation. It stimulates collagen synthesis while inhibiting collagenase activity, thereby preserving skin integrity and reducing visible signs of aging. Furthermore, it inhibits tyrosinase, addressing hyperpigmentation for a brighter, more even skin tone. This extract also fortifies the skin barrier by boosting moisture retention, offers anti-inflammatory relief, and exhibits antibacterial action against *Propionibacterium acnes*. Its protective actions extend to increasing antioxidative enzyme activity, neutralizing reactive oxygen species (ROS), safeguarding keratinocytes and dermal fibroblasts from UV damage, and stimulating the endogenous production of hyaluronic acid.


Research

Low confidence
Effective range N/A
Optimal

1%


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 4 – 6
0 7 14

Stability

The optimal pH range of 4.0-6.0 is inferred from Panax Ginseng Root Extract, a closely related species. For optimal stability, it should be incorporated into formulations when the temperature is below 50°C, or it can be directly added to the water phase during cold-processing.


Safety

CIR Status
Safe as used
Max tested
1%
Sensitization risk Low

The CIR Expert Panel concluded that Panax spp. root-derived ingredients, including Panax quinquefolius root extract, are safe for use in cosmetics. A specific Panax quinquefolius electrokinetic extract was rigorously assessed as safe for use up to 1% in personal care products. Human Repeat Insult Patch Testing (HRIPT) at 100% concentration confirmed it is neither irritating nor sensitizing to skin. In vitro tests further supported its non-irritating profile for skin (100% concentration) and eyes (10% concentration), with no observed phototoxicity.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

This multifaceted extract offers significant antioxidant, anti-aging, and skin-brightening benefits, suitable for all skin types due to its low irritancy and comedogenicity profile.


Related

Finding similar ingredients…


References