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PANAX GINSENG ROOT OIL.

Valuable CAS 50647-08-0 / SKIN CONDITIONING

Panax Ginseng Root Oil, frequently referred to as Red Ginseng Oil (RGO), is a potent lipid-soluble botanical extract valued for its diverse dermatological benefits. It delivers significant antioxidant and anti-inflammatory action, promoting skin hydration, collagen synthesis, and barrier repair.

Antioxidant Anti-inflammatory Moisturizing Collagen-boosting Skin barrier support Hair growth promotion Scalp conditioning Sebum regulation Skin brightening Skin conditioning

Science

This oil functions through multiple precise mechanisms to enhance skin health. It exhibits robust antioxidant properties by neutralizing free radicals and upregulating primary antioxidant enzymes like catalase (CAT), superoxide dismutase 2 (SOD2), and glutathione peroxidase (GPx). Its anti-inflammatory capabilities are mediated by suppressing nuclear factor κB (NF-κB) and activator protein 1 (AP-1) activation, thereby reducing the expression of pro-inflammatory mediators such as cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS), and cytokines including interleukin (IL)-1β, IL-6, and TNF-α. Furthermore, it stimulates collagen production, improves skin texture and firmness, and aids in restoring the skin's natural protective barrier. For the scalp, it supports healthy hair growth by activating dermal papilla cells, prolonging the anagen phase of hair follicles, enhancing local blood circulation, and regulating sebum production. It also possesses the potential to inhibit tyrosinase activity, which may lead to melanin suppression and brighter skin, while also preventing collagen degradation.


Research

Medium confidence
Effective range 1–10%
Optimal

N/A

Key findings

  1. 01 Topical application of a moisturizer containing 1% Red Ginseng Oil significantly improved skin moisture content in female volunteers aged 20-30.
  2. 02 A supercritical CO2-extracted Red Ginseng Oil formula, applied topically for 12 weeks, demonstrated no adverse effects in human volunteers.

Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

As a group of lipid-soluble phytochemicals rich in unsaturated fatty acids, Panax Ginseng Root Oil (RGO) components, particularly polyacetylenes, are known for chemical instability and a tendency to undergo oxidation. Its exact chemical composition can vary significantly based on the extraction method employed.


Safety

CIR Status
Not reviewed
Max tested
10%
Sensitization risk Low

The CIR report for Panax spp. root-derived ingredients does not specifically detail uses for Panax Ginseng Root Oil. However, Red Ginseng Oil (RGO), considered synonymous in many contexts, is generally regarded as safe and nontoxic. A clinical study demonstrated no adverse effects with topical application of a 10% RGO formula over 12 weeks. Adverse events associated with Panax ginseng monopreparations are rare, typically mild, and transient.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Panax Ginseng Root Oil is a valuable ingredient, offering comprehensive antioxidant, anti-inflammatory, and moisturizing benefits suitable for a wide range of skin types with a low risk of irritation.


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