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Moumoujus

PANAX GINSENG ROOT EXTRACT.

Valuable CAS 84650-12-4 / HAIR CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING, TONIC

Panax Ginseng Root Extract is a potent botanical known for its multifaceted benefits, including robust antioxidant defense against environmental stressors, enhanced skin hydration, and visible improvements in skin firmness and texture. It promotes a revitalized, healthy-looking complexion with improved elasticity.

Summary

Antioxidant Skin-Protecting Emollient Humectant Soothing Tonic

Science

Mechanism of Action

This extract delivers a rich complex of antioxidant compounds, such as various flavonoids, B vitamins, and ginsenosides, which actively neutralize free radicals and mitigate oxidative damage. It supports skin health by boosting hydration levels, refining skin texture, and promoting an even tone. By stimulating collagen synthesis, it helps to bolster skin firmness and reduce the appearance of fine lines. Furthermore, it enhances microcirculation, increasing the delivery of oxygen and nutrients to skin cells, contributing to a radiant glow. The extract also exhibits anti-inflammatory properties, inhibits reactive oxygen species (ROS) formation, protects cells from UV radiation damage, and can modulate melanin production for potential skin-brightening effects. It supports cellular renewal by inducing dermal papilla cell differentiation and suppressing apoptosis.

Research

Clinical Evidence

High confidence
Effective range 0.5–2%
Optimal

0.5%

Key findings

  1. 01 In an in vitro study, Panax Ginseng Root Extract at 50 μg/mL demonstrated significant anti-inflammatory effects, suppressing IL-1α by 34.17%, PGE2 by 20.70%, and NF-κB activation by 43.65%. This concentration also remarkably reduced reactive oxygen species (ROS) levels by 51.6% under oxidative stress conditions, indicating strong anti-carbonylation activity.

Transparency

Dusting Analysis

Commonly dusted
Min. effective
0.5%
Red flag below
0.5%

While recommended dosages for skincare and haircare span 0.5% to 2%, the CIR Expert Panel's maximum reported concentration for Panax Ginseng Root Extract in leave-on products is 0.5%. Formulations exceeding this 0.5% threshold might be considered 'dusting' from a regulatory perspective, as these higher concentrations fall outside the established maximum reported use levels for cosmetic safety by the CIR panel.

The Formula

Formulation

Solubility
Water
Optimal pH 6 – 8
0 7 14

Stability

This water-soluble extract maintains optimal stability and minimizes the degradation of key ginsenosides (e.g., Rg1, Rb1) within a pH range of 6.0 to 8.0. For optimal integration, it should be incorporated into formulations when the temperature is below 50°C. Storage below 25°C is recommended to preserve its bioactive compounds.

Conflicts

  • Veratrum nigrum

Safety

Safety Profile

CIR Status
Safe as used
Max tested
0.5%
Sensitization risk Low

The CIR Expert Panel has concluded that Panax spp. root-derived ingredients, including Panax Ginseng Root Extract, are safe in cosmetic practices of use and concentration. The maximum reported concentration for leave-on products is 0.5%, and 0.3% for rinse-off products. It is generally well-tolerated with few reported side effects. While considered non-irritating, patch testing is advisable due to individual sensitivities. The FDA clarifies that the term 'ginseng' on product labels must refer to plants classified within the genus Panax.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Panax Ginseng Root Extract is a valuable ingredient, leveraging its potent antioxidant, anti-inflammatory, and revitalizing properties to enhance skin's resilience, firmness, and radiance across all skin types within recommended usage parameters.

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