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PANAX GINSENG LEAF/STEM POWDER.

Valuable / SKIN CONDITIONING

Panax Ginseng Leaf/Stem Powder, rich in bioactive ginsenosides, provides robust antioxidant protection against environmental stressors, fostering cellular regeneration and enhancing skin vitality. Clinically demonstrated to reduce wrinkle depth, it additionally improves skin texture, elasticity, and barrier function for comprehensive skin health.

Summary

Skin Conditioning Antioxidant Protection Anti-aging Support Skin Regeneration Collagen Synthesis Promotion Elasticity Enhancement Barrier Strengthening Hydration Support Anti-inflammatory Action Skin Brightening UV Damage Protection (Cellular)

Science

Mechanism of Action

This ingredient primarily functions through its bioactive compounds, notably ginsenosides, which act as powerful antioxidants to neutralize free radicals and protect against environmental damage. It actively stimulates skin regeneration, leading to improved texture and elasticity, and strengthens the skin's natural barrier. Furthermore, it aids in reducing inflammation, boosts hydration, and optimizes skin nutrition and metabolism by enhancing subcutaneous capillary blood circulation and adjusting the skin's water balance. At a cellular level, it promotes collagen synthesis via the activation of transforming growth factor-β (TGF-β) in human skin fibroblast cells and prevents collagen destruction. It also offers protection against UV-induced damage, inhibits melanin production for a brightening effect, and encourages skin renewal by inducing the differentiation of dermal papilla cells.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 A purified extract from Panax ginseng leaves, standardized to specific ginsenoside concentrations (Rb3 ≥ 55%, Rb2 ≥ 12%), demonstrated a significant reduction in deep furrow depth in crow's feet wrinkles over an eight-week clinical period, without inducing primary skin irritation.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 6 – 7.4
0 7 14

Stability

The active ginsenosides are extremely susceptible to thermal degradation during drying, storage, heating, and extraction processes. They exhibit instability in acidic conditions, with optimal stability for key ginsenosides (Rg1 and Rb1) identified at approximately pH 6.0, extending to pH 7.4 in alkaline and phosphate buffer systems.

Conflicts

  • strong acids
  • high heat processing

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While the Cosmetic Ingredient Review (CIR) Expert Panel has assessed Panax spp. root-derived ingredients as safe for cosmetic use, a direct safety review for 'PANAX GINSENG LEAF/STEM POWDER' or its specific extract is not available. However, clinical studies have shown no primary skin irritation in humans, suggesting it is generally safe and well-tolerated.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Panax Ginseng Leaf/Stem Powder is a valuable multi-functional ingredient, clinically proven for anti-aging and supported by robust mechanistic data, offering antioxidant, regenerative, and brightening benefits across all skin types.

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