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PANAX GINSENG LEAF/ROOT/STEM EXTRACT.

Valuable / ANTIOXIDANT

Panax Ginseng Leaf/Root/Stem Extract is a versatile botanical powerhouse, rich in bioactive ginsenosides, revered for its comprehensive skin benefits. It actively promotes collagen synthesis, enhances cellular vitality, and offers significant antioxidant and anti-inflammatory protection, contributing to a visibly rejuvenated and even-toned complexion.

Summary

Antioxidant Anti-inflammatory Collagen synthesis booster Skin firming Elasticity enhancer Wrinkle reduction Skin brightening Hyperpigmentation reduction Skin hydration Skin barrier strengthening Skin regeneration Skin texture refining Promotes microcirculation Skin conditioning

Science

Mechanism of Action

This extract, abundant in bioactive ginsenosides (such as F2, Rb3, and Rb2), acts as a potent antioxidant by inhibiting Reactive Oxygen Species (ROS) and boosting natural anti-oxidative enzymes, thus safeguarding skin from environmental damage. It also exhibits anti-inflammatory properties, providing a soothing effect. Key to its age-defying action, Panax Ginseng supports collagen integrity and synthesis by suppressing collagenase, an enzyme responsible for collagen breakdown, and stimulating transforming growth factor-β (TGF-β) in human dermal fibroblasts. This multifaceted action improves skin firmness, elasticity, and diminishes the appearance of wrinkles. Furthermore, it aids in skin brightening through tyrosinase inhibition, reducing hyperpigmentation, while also enhancing hydration, strengthening the skin barrier, and promoting microcirculation for improved nutrient delivery and regeneration.

Research

Clinical Evidence

High confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Purified Panax ginseng leaf extracts at 100 µg/mL increased collagen synthesis by 55.1% in human dermal fibroblasts.
  2. 02 Ginsenoside Rb3 at 100 µM significantly boosted Type I collagen production by 160.2%.
  3. 03 Topical application of a Panax Ginseng Leaf Purified Extracts lotion demonstrably reduced crow's feet wrinkle depth over an eight-week period.
  4. 04 Panax ginseng extract at 10 ng/ml maximally stimulated human dermal fibroblast proliferation and collagen synthesis.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

This extract is soluble in water at 80°C and readily dissolves in ethanol. For optimal stability, it should be stored in a cool, dry environment away from direct light.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
0.1%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has deemed Panax spp. root-derived ingredients safe at their current uses and concentrations. While generally well-tolerated, rare instances of allergic reactions, skin rashes, itching, or irritation may occur with topical application, suggesting a patch test for individuals with sensitive skin. The FDA does not typically 'approve' cosmetic ingredients, though product listings may reference 'FDA Standard'. A max concentration of 0.1% has been noted for related Panax ginseng root extract in some historical uses.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Panax Ginseng Leaf/Root/Stem Extract is a valuable multi-functional ingredient, clinically shown to boost collagen, reduce wrinkles, and provide comprehensive antioxidant protection for various skin types.

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