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Moumoujus

PANAX GINSENG LEAF CELL EXTRACT.

Valuable

Panax Ginseng Leaf Cell Extract harnesses the potent bioactives, including ginsenosides, from the ginseng leaf to deliver multifaceted benefits. This ingredient is engineered to rejuvenate and protect the skin, enhancing its resilience, elasticity, and overall vitality.

Summary

Antioxidant Collagen Booster Anti-aging Anti-inflammatory Hydrating Skin Regeneration Wound Healing Melanin Inhibition (potential) Antibacterial (potential)

Science

Mechanism of Action

This extract operates through several key pathways. Its primary active compounds, ginsenosides, function as robust antioxidants, neutralizing free radicals and shielding skin cells from environmental stressors and premature aging. It notably stimulates Type I collagen synthesis in human skin fibroblasts, partly by engaging the transforming growth factor-β (TGF-β) pathway, which is essential for maintaining skin's structural integrity. Additionally, it exhibits anti-inflammatory properties, promoting a calmer complexion, and supports barrier function to enhance skin hydration. Emerging research also indicates potential roles in regulating melanin production and offering antibacterial benefits against C. acnes.

Research

Clinical Evidence

High confidence
Effective range 0.01–0.05%
Optimal

For collagen synthesis, 0.01% has shown significant efficacy. For visible wrinkle reduction, 0.05% has demonstrated positive results.

Key findings

  1. 01 A 0.01% concentration (100µg/mL) of Panax ginseng extract was observed to significantly increase Type I collagen synthesis by 55.1% in human skin fibroblasts.
  2. 02 A cosmetic formulation incorporating 0.05% ginseng extract, applied to the periocular area for 8 weeks, resulted in a significant improvement in fine lines and crow's feet.
  3. 03 Purified Panax ginseng leaf extracts (PGLE), rich in ginsenoside Rb3, were clinically validated to decrease the depth of deep furrows (crow's feet) over an eight-week duration.

Transparency

Dusting Analysis

Not commonly dusted

No specific data provided regarding common dusting practices or thresholds for this ingredient.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed (specifically leaf cell extract)
Sensitization risk Low

While the Cosmetic Ingredient Review (CIR) Expert Panel has not directly reviewed Panax ginseng leaf cell extract, related Panax spp. root-derived ingredients are deemed 'safe in the practices of use and concentration'. General consensus indicates high safety for leaf-stem extracts, with one study reporting no primary skin irritation in human subjects. For Panax Ginseng Root Extract, individual patch testing is occasionally recommended due to potential sensitivities.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Panax Ginseng Leaf Cell Extract is a valuable ingredient, clinically demonstrated to boost collagen, reduce wrinkles, and offer broad protective and regenerative benefits for diverse skin types.

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