Science
Mechanism of Action
This extract operates on multiple levels to comprehensively support skin health and resilience. It actively strengthens the skin's natural barrier, offering protection from environmental aggressors such as pollution and UV radiation, which are known contributors to premature aging. Its potent antioxidant properties enable it to effectively neutralize free radicals and inhibit the formation of reactive oxygen species (ROS) within skin cells, preventing oxidative damage. At a cellular level, it stimulates dermal fibroblasts to synthesize essential collagens (primarily Type I and Type III) and helps combat skin sagging by activating the transforming growth factor-β (TGF-β) pathway, crucial for maintaining skin strength. Furthermore, the extract promotes natural regeneration functions, supports skin hydration by forming a protective film to limit transepidermal water loss, facilitates wound healing, and contributes to a brighter complexion by inhibiting melanin production.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 An *in vitro* study demonstrated a 55.1% increase in collagen synthesis within human dermal fibroblasts when treated with 100 µg/mL of the extract.
- 02 Topical application of a Panax ginseng leaf extract (PGLE) lotion in human subjects resulted in a measurable decrease in the depth of deep furrows in the crow's feet wrinkle region over an eight-week treatment period.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Optimal stability for key ginsenosides (Rg1 and Rb1) is observed at a precise pH of 6. The extract exhibits good solubility in water and is also easily soluble in ethanol.
Safety
Safety Profile
While generally considered safe and well-tolerated for topical use, rare instances of mild allergic reactions, sensitivity, skin rashes, itching, or irritation have been reported, necessitating a patch test prior to widespread application. It is important to note that the Cosmetic Ingredient Review (CIR) has not specifically evaluated the safety of extracts derived from the flower, leaf, or stem of Panax ginseng, with existing CIR assessments typically focusing solely on root-derived ingredients.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Panax Ginseng Flower/Leaf/Stem Extract is a valuable multi-active ingredient that significantly enhances skin resilience, boosts collagen, and offers robust antioxidant and regenerative benefits across all skin types.
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