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PANAX GINSENG BERRY EXTRACT.

Valuable CAS 84650-12-4 / SKIN CONDITIONING, SKIN PROTECTING

Panax Ginseng Berry Extract is a potent botanical known for its multifaceted benefits, primarily its robust antioxidant and anti-aging properties. It actively works to mitigate oxidative stress, support skin firmness and elasticity, and diminish hyperpigmentation, contributing to a revitalized and visibly brighter complexion.

Summary

antioxidant skin conditioning anti-aging brightening wound healing support anti-inflammatory barrier repair collagen support elasticity improvement hydrating

Science

Mechanism of Action

This extract enhances skin health through several precise pathways. It delivers potent antioxidant effects against oxidative stress and effectively reduces MMP-1 overexpression, an enzyme associated with collagen degradation induced by UV exposure. Panax Ginseng Berry Extract has been shown to increase hyaluronic acid production in HaCaT keratinocytes, thus boosting skin hydration. Furthermore, it exerts antimelanogenic effects by reducing melanin accumulation and tyrosinase activity, primarily by activating the FoxO3a signaling pathway, which also contributes to its anti-aging capabilities. Rich in bioactive compounds such as ginsenosides, phenolic compounds, and polysaccharides, it aids in wound healing processes, functions as an anti-inflammatory agent, supports the skin's natural collagen synthesis, and improves overall barrier repair and protection.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In vitro wound healing assays using keratinocytes demonstrated that higher concentrations of ginseng berry marc extract (2.5, 5, and 10 mg/mL) resulted in a proportionally higher rate of cellular healing.
  2. 02 An in vitro study of ginseng fruit marc ethanol extract at concentrations of 0.25 and 0.5 mg/mL showed excellent cell viability, exceeding a 90% survival rate, alongside significant antioxidant effects.
  3. 03 Ginseng berry extract reduced melanin accumulation and tyrosinase activity in human melanoma MNT1 cells, confirming its antimelanogenic effects through FoxO3a activation.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 4 – 6
0 7 14

Stability

The optimal pH range of 4.0-6.0 is reported for Panax Ginseng Root Extract and is generally considered a suitable guideline for other ginseng extracts. While specific optimal stability pH for the berry extract is not explicitly stated, a pH of 6.0 has been utilized for analytical purposes.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Although the Cosmetic Ingredient Review (CIR) Expert Panel has not specifically assessed Panax Ginseng Berry Extract, related ingredients like Panax Ginseng Root and Root Extract are deemed safe for cosmetic applications. Its inclusion as a cosmetic ingredient in Europe indicates compliance with EU safety regulations. General Panax ginseng varieties consistently exhibit a very safe profile in clinical trials, with any reported adverse events typically being mild and transient.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Panax Ginseng Berry Extract is a valuable ingredient, demonstrating significant antioxidant, anti-aging, and skin-brightening benefits through promising in vitro research, rendering it suitable for a comprehensive range of skin types.

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