Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

PALMITOYL TRIPEPTIDE-5 AMIDOPROPYL ASCORBYL PHOSPHATE HCL.

Insufficient Data / SKIN CONDITIONING

This innovative hybrid molecule combines a collagen-stimulating peptide, Palmitoyl Tripeptide-5, with Amidopropyl Ascorbyl Phosphate HCl, a stabilized derivative of Vitamin C. It is engineered to enhance skin texture, reduce wrinkle depth, and deliver antioxidant protection.

Summary

skin conditioning antioxidant collagen boosting improving skin texture

Science

Mechanism of Action

PALMITOYL TRIPEPTIDE-5 AMIDOPROPYL ASCORBYL PHOSPHATE HCL functions via a dual-action pathway. The Palmitoyl Tripeptide-5 segment actively stimulates transforming growth factor-β (TGF-β), a key signaling molecule that promotes the synthesis of collagen types I and III by dermal fibroblasts. This peptide also appears to inhibit matrix metalloproteinase 1 and 3 (MMP1 and MMP3) activity, enzymes known to degrade collagen, thereby supporting the skin's natural repair mechanisms and boosting collagen production. Concurrently, the Amidopropyl Ascorbyl Phosphate HCl component, a highly stable derivative of ascorbic acid (Vitamin C), provides potent antioxidant benefits and contributes to further collagen synthesis, improving overall skin conditioning and resilience.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 5 – 7
0 7 14

Stability

Engineered as a derivative of ascorbic acid, this ingredient demonstrates enhanced stability and efficacy compared to traditional Vitamin C, making it suitable for a diverse range of skincare formulations. An optimal pH range of 5.0 to 7.0 is recommended for its peptide component.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel has assessed Palmitoyl Tripeptide-5 and related Vitamin C derivatives (e.g., Ascorbyl Glucoside up to 5%) as safe in cosmetics. However, this specific combined ingredient, PALMITOYL TRIPEPTIDE-5 AMIDOPROPYL ASCORBYL PHOSPHATE HCL, has not undergone a dedicated safety assessment by CIR or SCCS, leaving its specific maximum safe concentration unestablished. Safety is currently extrapolated from its individual, reviewed components.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

This hybrid ingredient holds promising potential due to its established collagen-stimulating peptide and stable antioxidant Vitamin C derivative, yet specific clinical efficacy and comprehensive safety assessments for the combined molecule are currently unavailable.

Related

Similar Ingredients

Finding similar ingredients…