Science
Mechanism of Action
This synthetic peptide, identified as palmitoyl-glycine-proline-hydroxyproline, functions by emulating the Gly-Pro-Hyp motif found within natural collagen type I. This biomimetic action signals to the skin that collagen has been depleted, thereby stimulating the synthesis of new collagen. The integrated palmitoyl modification is crucial for improving the peptide's skin penetration and overall stability.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Human clinical studies have demonstrated that cosmetic products containing Palmitoyl Tripeptide-29 lead to significant improvements in skin wrinkles and elasticity, confirming an anti-aging effect on human facial skin after 8 weeks of consistent use.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The peptide solution should be introduced into the water phase of a formulation and maintains stability up to 50°C. For raw material storage, temperatures between 2–8°C are recommended, and heating above 40°C should be meticulously avoided during the emulsification process to prevent degradation.
Conflicts
- strong acids
- strong bases
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has assessed Palmitoyl Oligopeptides, a group including Palmitoyl Tripeptide-29, concluding their safety for cosmetic use at typical concentrations below 10 ppm. Notably, Palmitoyl Tripeptide-29 itself is reported to possess zero antigenicity or allergenic potential.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Palmitoyl Tripeptide-29 is a valuable and well-tolerated peptide, clinically proven to enhance collagen production and improve skin's elasticity and wrinkle appearance, making it a robust anti-aging component suitable for all skin types.
Related
Similar Ingredients
Finding similar ingredients…