Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

PALMITOYL SH-TRIPEPTIDE-3 AMIDE.

Valuable / HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

This advanced lipo-peptide is engineered to precisely mimic Epidermal Growth Factor (EGF), stimulating cellular regeneration and vital protein synthesis. It is designed to enhance skin elasticity, visibly reduce the appearance of wrinkles, and promote a firmer, more radiant complexion.

Summary

Skin-conditioning agent Humectant Skin-protecting Anti-aging Collagen booster Elastin booster Cell growth promoter Skin repair

Science

Mechanism of Action

As a low molecular weight lipo-peptide derived from Pro-EGF, Palmitoyl sh-Tripeptide-3 Amide targets and binds to the Epidermal Growth Factor Receptor (EGFR). This specific binding initiates a cascade of cellular activities, promoting the robust growth, proliferation, and differentiation of both keratinocytes and dermal fibroblasts. Crucially, it significantly upregulates the endogenous production of essential structural proteins such as collagen and elastin, while also actively attracting reparative cells to sites of micro-damage. This multifaceted action supports comprehensive skin repair, improves firmness, and diminishes the visible signs of aging. Additionally, it functions as a humectant and skin-protecting agent.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

1.2%

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

The inclusion of a palmitoyl group and amide modification contributes to enhanced stability within diverse cosmetic formulations.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically evaluated Palmitoyl sh-Tripeptide-3 Amide under its exact name. However, related palmitoyl oligopeptides and tripeptide amides have been reviewed and deemed safe for cosmetic use, with some derivatives noted as safe below 0.001%. This ingredient is generally considered safe for use in cosmetic products when incorporated according to established guidelines.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Palmitoyl sh-Tripeptide-3 Amide is a valuable EGF-mimicking peptide, offering significant benefits for skin regeneration, collagen and elastin synthesis, and overall anti-aging improvement.

Related

Similar Ingredients

Finding similar ingredients…