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PALMITOYL SH-TRIPEPTIDE-2 AMIDE.

Insufficient Data / HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

PALMITOYL SH-TRIPEPTIDE-2 AMIDE is a low molecular weight lipo-peptide, structurally derived from the Tumor Necrosis Factor Receptor (TNFR). Its primary action involves targeting and inhibiting Tumor Necrosis Factor-α (TNF-α), a key mediator in inflammatory skin responses, to deliver a soothing and anti-inflammatory effect.

Anti-inflammatory Soothing

Science

This lipo-peptide functions as a direct antagonist to Tumor Necrosis Factor-α (TNF-α), a potent pro-inflammatory cytokine. By competitively binding or inhibiting TNF-α, PALMITOYL SH-TRIPEPTIDE-2 AMIDE effectively neutralizes a significant pathway of skin inflammation, leading to a reduction in irritation and a pronounced soothing action upon topical application.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Unknown
Optimal pH N/A
0 7 14

Safety

CIR Status
Not reviewed
Sensitization risk Unknown

Specific, independent safety assessments from regulatory bodies such as the Cosmetic Ingredient Review (CIR), Scientific Committee on Consumer Safety (SCCS), or the U.S. Food and Drug Administration (FDA) have not been located for PALMITOYL SH-TRIPEPTIDE-2 AMIDE. While broader reviews exist for the general class of palmitoyl peptides, these do not explicitly cover the safety profile of this distinct ingredient.


Your Skin

No Normal
No Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

Possessing a clear anti-inflammatory mechanism, the overall evaluation for PALMITOYL SH-TRIPEPTIDE-2 AMIDE is hampered by the current absence of specific clinical efficacy studies and detailed independent safety assessments.


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