Science
Mechanism of Action
This lipo-peptide functions as a direct antagonist to Tumor Necrosis Factor-α (TNF-α), a potent pro-inflammatory cytokine. By competitively binding or inhibiting TNF-α, PALMITOYL SH-TRIPEPTIDE-2 AMIDE effectively neutralizes a significant pathway of skin inflammation, leading to a reduction in irritation and a pronounced soothing action upon topical application.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
Specific, independent safety assessments from regulatory bodies such as the Cosmetic Ingredient Review (CIR), Scientific Committee on Consumer Safety (SCCS), or the U.S. Food and Drug Administration (FDA) have not been located for PALMITOYL SH-TRIPEPTIDE-2 AMIDE. While broader reviews exist for the general class of palmitoyl peptides, these do not explicitly cover the safety profile of this distinct ingredient.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Possessing a clear anti-inflammatory mechanism, the overall evaluation for PALMITOYL SH-TRIPEPTIDE-2 AMIDE is hampered by the current absence of specific clinical efficacy studies and detailed independent safety assessments.
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References
Sources