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Moumoujus

PALMITOYL SH-TETRAPEPTIDE-2 AMIDE.

Valuable / SKIN CONDITIONING

This lipo-peptide targets inflammatory responses by specifically inhibiting the Interleukin-1R receptor, a key mediator of irritation. It is designed to alleviate skin sensitivity, reduce inflammation, and combat hypersensitivity reactions effectively.

Summary

Anti-inflammatory Soothing Hypersensitivity Reduction

Science

Mechanism of Action

Palmitoyl sh-Tetrapeptide-2 Amide functions as a biomimetic lipo-peptide. Its unique sequence, Pal-Lys‑Asn‑Val‑Arg-NH2, acts by mimicking a fragment of the human Interleukin-1 receptor type 1 (IL-1R). This targeted inhibition of the Interleukin-1R inflammatory cytokine receptor intervenes in pro-inflammatory pathways, thereby soothing skin irritation and exhibiting a pronounced anti-inflammatory effect. The manufacturer notes its ability to reduce hypersensitivity and allergic skin responses.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Comprehensive regulatory safety evaluations from bodies such as CIR, SCCS, or FDA are currently not available for Palmitoyl sh-Tetrapeptide-2 Amide. Its safety rating remains unclassified by several reputable databases, including Paula's Choice.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Palmitoyl sh-Tetrapeptide-2 Amide is a valuable ingredient for mitigating skin irritation and hypersensitivity due to its specific anti-inflammatory mechanism of inhibiting the Interleukin-1R receptor.

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