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PALMITOYL OLIVE LEAF EXTRACT.

Valuable CAS - / ANTIOXIDANT

Palmitoyl Olive Leaf Extract is an oil-soluble derivative celebrated for its potent antioxidant and anti-inflammatory properties. This versatile ingredient deeply hydrates, supports collagen, and offers photoprotection, making it valuable for comprehensive skin rejuvenation and maintaining barrier health across all skin types.

Antioxidant Anti-inflammatory Moisturizing Anti-aging Skin Conditioning Photoprotective Antimicrobial Wound Healing Support Hyperpigmentation Reduction

Science

Leveraging the rich polyphenols, flavonoids, and oleuropein inherent to olive leaf, Palmitoyl Olive Leaf Extract acts as a powerful antioxidant, neutralizing free radicals to mitigate premature aging. Its anti-inflammatory action is demonstrated by the suppression of pro-inflammatory mediators such as TNF-α, IL-6, IL-1β, nitric oxide, prostaglandin E2, and reactive oxygen species, alongside promoting the shift of M1 to less inflammatory M2 macrophages. The ingredient enhances skin hydration by reducing transepidermal water loss (TEWL) and boosting moisture levels. It also supports collagen production, thereby minimizing fine lines and improving overall skin texture. Additional benefits include photoprotection against UVB-induced damage through melanin regulation and enzyme inhibition, antimicrobial effects for acne management, and potential support for wound healing and hyperpigmentation reduction.


Research

Medium confidence
Effective range 0.1–1%
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH 4.8 – 5.2
0 7 14

Stability

Optimal stability for oleuropein, a key active component within olive leaf extracts, is approximately pH 5. High temperatures (e.g., 110°C) significantly degrade oleuropein content, and storage at 25°C is less stable than at -20°C. Incorporation into specific delivery systems or encapsulation can enhance its overall stability.


Safety

CIR Status
Safe as used
Max tested
2%
Sensitization risk Low

The CIR Expert Panel deemed 16 Olea europaea (olive)-derived ingredients, including Olea europaea (Olive) Leaf Extract, safe for cosmetic use, with reported concentrations up to 2% in leave-on formulations such as suntan preparations. While Palmitoyl Olive Leaf Extract is listed in CIR meeting documents, a specific standalone safety assessment for this exact palmitoylated form is not yet available; however, it is generally considered within the broader olive-derived ingredient safety profile. Clinical studies involving olive leaf extract-containing skin lotions have reported no adverse effects.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Palmitoyl Olive Leaf Extract is a valuable, multifaceted ingredient offering significant antioxidant and anti-inflammatory benefits, enhancing skin hydration, promoting rejuvenation, and supporting overall skin health across various skin types.


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