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PALMITOYL OLIGOPEPTIDE-135.

Insufficient Data / SKIN CONDITIONING

PALMITOYL OLIGOPEPTIDE-135 is a synthetic peptide engineered to act as a skin conditioning agent. It aims to maintain optimal skin health by supporting the skin's intrinsic regenerative capabilities, contributing to a refined and resilient complexion.

Skin Conditioning Anti-aging Skin Regeneration Skin Firming Elasticity Enhancer

Science

This oligopeptide functions as a signal to the skin, activating its natural repair mechanisms. By promoting cellular regeneration and strengthening the skin's structural integrity, it works to visibly diminish the appearance of wrinkles, thereby enhancing overall skin complexion and elasticity.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 4 – 6
0 7 14

Stability

For optimal stability, this peptide should be incorporated into formulations during the final processing stages, at a temperature below 45°C, ideally maintained under 40°C.

Conflicts

  • Direct acids
  • Retinoids
  • Strong antioxidants (e.g., Vitamin C)

Safety

CIR Status
Insufficient data
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel determined there was insufficient data to adequately evaluate 'Palmitoyl Oligopeptide' as a specific ingredient, noting that the generalized term could refer to various distinct peptide sequences. Consequently, there is no dedicated safety assessment for PALMITOYL OLIGOPEPTIDE-135. While the broader 'Palmitoyl oligopeptide' category is reported in the FDA's Voluntary Cosmetic Registration Program, no specific SCCS review for this particular ingredient was found.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

While PALMITOYL OLIGOPEPTIDE-135 presents a promising mechanism for skin conditioning and anti-aging, the absence of specific clinical studies and comprehensive safety data for this particular peptide sequence leads to an insufficient data rating, warranting further evaluation.


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