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PALMITOYL DIPEPTIDE-5 DIAMINOBUTYROYL HYDROXYTHREONINE.

Valuable CAS - / SKIN CONDITIONING

PALMITOYL DIPEPTIDE-5 DIAMINOBUTYROYL HYDROXYTHREONINE is a sophisticated synthetic signal peptide engineered to fortify the skin's dermal-epidermal junction. It actively promotes enhanced elasticity, firmness, and overall skin smoothness, visibly reducing the appearance of lines and improving overall skin tone.

Anti-aging Skin-conditioning

Science

This advanced synthetic signal peptide targets the dermal-epidermal junction (DEJ), the crucial interface between the dermis and epidermis. By simultaneously stimulating key structural proteins such as Laminin V, Collagen types IV, VII, and XVII, and Integrin, it works to restore optimal DEJ function. This action improves molecular communication and structural integrity, thereby enhancing skin elasticity, firmness, and suppleness and activating the skin's natural repair mechanisms.


Research

High confidence
Effective range 1–3%
Optimal

N/A

Key findings

  1. 01 Clinical trials demonstrate that formulations incorporating 1-3% of this peptide, particularly when combined with other peptides, lead to visible enhancements in skin tone, firmness, and smoothness.
  2. 02 Users have reported improved skin tonicity and suppleness, along with a reduction in visible lines, within two months of consistent application.

Transparency

Not commonly dusted

The Formula

Solubility
Unknown
Optimal pH N/A
0 7 14

Stability

This peptide is often integrated into patented complexes like SYN®-TACKS CB, which are designed for ease of formulation, are TFA-free, and typically do not require additional preservatives. Its efficacy is frequently amplified when combined with other peptides, creating a synergistic effect.

Synergies

  • Other peptides (for enhanced performance)

Safety

CIR Status
Not reviewed
Sensitization risk Low

While a specific CIR safety assessment for this particular peptide is not available, general reviews for broader protein and peptide categories affirm its safety profile. It is widely regarded as safe and non-irritating across all skin types, with EWG Skin Deep classifying it with low concerns for various toxicities.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

This peptide is a valuable asset in precision skincare, effectively enhancing dermal-epidermal junction integrity to improve skin firmness, elasticity, and reduce visible lines.


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