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Ingredient directory

Palmitamine Oxide

Palmitamine Oxide is a multi-functional zwitterionic surfactant extensively used in skincare for its mild cleansing and conditioning properties. It effectively generates stable foam and can mitigate irritation often associated with other surfactants, making it suitable for a wide range of skin types.

Directory entry · Individual source review pending

This profile is awaiting an individual source review. Treat its ratings, dose estimates and compatibility labels as provisional; they are not medical advice or proof of a finished product’s effects.

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Science

Mechanism of Action

As a zwitterionic surfactant, Palmitamine Oxide functions by altering surface tension, facilitating robust emulsification, dispersion, and wetting action essential for effective cleansing. It also acts as a foam booster and stabilizer, enhancing product aesthetics and efficacy. Critically, its mild nature contributes to reducing the irritant potential of other more aggressive cleansing agents.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Palmitamine Oxide exhibits broad pH stability, remaining stable without hydrolyzing in both acidic and alkaline environments. While generally considered water-soluble, its intrinsic solubility is precisely estimated at 0.03197 mg/L at 25 °C, indicating its effective function in aqueous systems despite this low concentration.

Synergies

  • Other surfactants (reduces irritation)

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The EPA has verified Palmitamine Oxide as being of low concern for cleaning products. Comprehensive reports from the OECD for amine oxides as a class indicate general safety, with no evidence of genotoxic, carcinogenic, reproductive, or developmental toxicity, nor dermal sensitization. When in paste form, it is noted for low irritation to both skin and eyes, and EWG also rates it with low concern for cancer, allergies & immunotoxicity, and developmental & reproductive toxicity.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Palmitamine Oxide is a valuable ingredient for its mild cleansing and conditioning capabilities, along with its ability to significantly reduce potential irritation from other surfactants, making it highly compatible with all skin types.

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