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Moumoujus

PAEONIA SUFFRUTICOSA EXTRACT.

Valuable CAS 223747-88-4 / SKIN CONDITIONING

Paeonia Suffruticosa Extract, derived from the Moutan Peony, is a multifaceted botanical active recognized for its significant antioxidant and anti-inflammatory properties. It actively supports skin health by protecting against environmental aggressors and promoting a more even, youthful complexion. This ingredient is well-suited for all skin types, including sensitive.

Summary

Skin protecting Antioxidant Soothing Skin conditioning Anti-inflammatory Anti-aging Photoprotective Hydrating Brightening Sebum regulating

Science

Mechanism of Action

This extract operates through multiple pathways to enhance skin vitality. Its rich content of flavonoids and polyphenols delivers potent antioxidant protection, effectively neutralizing free radicals and mitigating oxidative stress responsible for premature aging and hyperpigmentation. Anti-inflammatory benefits are achieved by modulating inflammatory factors such as IL-1α, IL-6, TRPV1, and histamine, alongside involvement in pathways like AMPK/PI3K/Akt/Nrf2, thereby reducing redness and irritation. Furthermore, it offers photoprotective and anti-aging effects by absorbing UV radiation, preventing collagen and elastin degradation, and influencing the IRS/PI3K/FOXO pathway to improve elasticity. It also contributes to balanced sebum production, enhanced hydration through humectant properties, and skin brightening via components like paeonol and paeoniflorin.

Research

Clinical Evidence

Medium confidence
Effective range 0.1%–1%%
Optimal

1%

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

One of its main active components, paeonol, is noted for poor water solubility, low stability, and high volatility at room temperature, which can be a formulation consideration.

Safety

Safety Profile

CIR Status
Insufficient data
Max tested
0.5%%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel concluded that available data were insufficient to determine the safety of Paeonia Suffruticosa Extract (and bark/root extracts) for cosmetic use. However, HRIPTs at concentrations up to 0.5% for Paeonia Suffruticosa Root Extract showed no irritation or sensitization. A reported maximum use concentration for Paeonia Suffruticosa Root Extract in specific applications like paste masks and mud packs is 0.5%. While generally considered safe for topical application, individuals with known plant sensitivities should perform a patch test prior to use.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Paeonia Suffruticosa Extract is a valuable botanical ingredient offering comprehensive benefits including collagen support, antioxidant defense, anti-inflammatory action, and improved skin hydration, making it suitable for a wide range of skin types.

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