Science
Mechanism of Action
This extract functions as a potent antioxidant, diligently neutralizing free radicals and safeguarding against oxidative stress. Its anti-inflammatory capacity effectively calms irritated skin, reducing redness and soothing conditions such as atopic dermatitis and psoriasis. By combating free radical damage, stimulating cell renewal, and inhibiting tyrosinase activity, it contributes to anti-aging and skin brightening by diminishing the appearance of dark spots, fine lines, and wrinkles. Furthermore, it supports the skin's barrier integrity and boosts epidermal moisture content, alongside inhibiting collagenase and hyaluronidase enzymes.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 Clinical investigations suggest Paeonia Suffruticosa Bark Extract confers antioxidant, anti-aging, and skin brightening benefits. While precise effective concentrations are currently undetermined, certain components, like paeonol, have demonstrated positive effects on chronic dermatitis, including atopic dermatitis and psoriasis.
- 02 Additional studies indicate an improvement in skin elasticity and overall moisture content following its application.
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Panel determined that there is insufficient data to ascertain the safety of Paeonia Suffruticosa Bark Extract, as well as related extracts. While Human Repeated-Insult Patch Tests (HRIPT) conducted on Paeonia Suffruticosa Root Extract at concentrations of 0.0015% (in a lotion) and 0.5% (in a face mask) showed no evidence of irritation or sensitization in 52 and 106 subjects respectively, these tests pertain to a related extract. The CIR Panel also articulated broader concerns regarding potential impurities in botanical ingredients, such as heavy metals and pesticide residues. Therefore, while related extracts have exhibited low irritation in specific safety assessments, definitive safety conclusions for Paeonia Suffruticosa Bark Extract require further data.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Paeonia Suffruticosa Bark Extract presents promising antioxidant, anti-inflammatory, and anti-aging benefits, however, the Cosmetic Ingredient Review (CIR) Panel has deemed safety data for the bark extract itself insufficient, necessitating cautious consideration in formulation.
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