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PAEONIA LACTIFLORA ROOT POWDER.

Valuable / ABRASIVE, HUMECTANT

Paeonia Lactiflora Root Powder is a multifunctional botanical extract renowned for its comprehensive skin benefits. Rich in active compounds like paeoniflorin, it functions as a potent antioxidant, helps to mitigate signs of aging, and promotes a more even, calm complexion.

Summary

antioxidant skin-conditioning soothing brightening anti-aging

Science

Mechanism of Action

This ingredient works through multiple pathways to enhance skin health. Its high concentration of flavonoids, polyphenols, and essential oils provides robust antioxidant defense, shielding the skin from environmental aggressors such as pollution, free radicals, and UV radiation. The active compound, paeoniflorin, stimulates mitophagy, a cellular process that optimizes energy production, detoxifies cells from reactive oxygen species (ROS), and boosts cellular resilience, contributing significantly to an anti-aging effect. Furthermore, it precisely targets uneven skin tone and pigmentation by modulating melanin synthesis and inhibiting tyrosinase activity. It also supports skin structure by promoting collagen production and improving elasticity. Its anti-inflammatory capabilities are evidenced by its ability to inhibit nitric oxide (NO) and other inflammatory factors, reduce ROS levels, and modulate the MAPK and NF-κB signaling pathways, effectively calming irritation and redness. Finally, it helps combat skin dullness by inhibiting Advanced Glycation End-product (AGE) formation, blocking AGE-RAGE binding, and restoring proper keratinocyte differentiation.

Research

Clinical Evidence

Medium confidence
Effective range 0.01–1%
Optimal

1%

Key findings

  1. 01 In vitro studies demonstrate that at 1-3% concentration, the active ingredient paeoniflorin triggers mitophagy, optimizing cellular energy and detoxification, leading to enhanced cellular resilience and an anti-aging effect.
  2. 02 Further in vitro research shows significant anti-inflammatory action, with a 0.05% concentration reducing IL-6 overproduction by 37.78% in LPS-induced inflammation models.
  3. 03 A 0.01% concentration also demonstrated anti-inflammatory effects, reducing IL-6 overproduction by 28.70% in LPS-induced inflammation.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

To preserve its beneficial compounds, the ingredient should be added during the cool-down phase of formulation, ideally below 40°C (104°F). Store in a cool, dry place, protected from light.

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
1%
Sensitization risk Low

While the Cosmetic Ingredient Review (CIR) has not specifically reviewed Paeonia Lactiflora Root Powder, related extracts are generally considered safe due to their natural origin. A safety assessment utilizing the Threshold of Toxicological Concern (TTC) approach has deemed Paeonia lactiflora root extract safe for cosmetic use at concentrations up to 1%. No notable side effects or intolerances have been reported to date.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Paeonia Lactiflora Root Powder is a valuable botanical ingredient, offering robust antioxidant protection, significant anti-aging benefits through cellular revitalization, and noticeable improvements in skin tone and inflammation.

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