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PAEONIA LACTIFLORA FLOWER EXTRACT.

Valuable / ANTIOXIDANT, SKIN PROTECTING

Paeonia Lactiflora Flower Extract is a botanical powerhouse, rich in bioactive compounds, offering a spectrum of benefits from robust antioxidant and anti-inflammatory protection to targeted skin brightening. This extract actively contributes to overall skin health by defending against environmental stressors, soothing irritation, and promoting a more even, youthful complexion.

Summary

Antioxidant Skin-soothing Anti-inflammatory Skin Brightening Anti-aging Hydrating

Science

Mechanism of Action

This extract, abundant in compounds like flavonoids, tannins, and paeoniflorin, functions as a potent antioxidant by neutralizing free radicals and mitigating oxidative stress, thus protecting against premature aging and UV-induced lipid peroxidation. Its anti-inflammatory action is achieved through inhibiting the release of nitric oxide (NO) and other inflammatory factors, reducing reactive oxygen species (ROS) levels, and deactivating key inflammatory signaling pathways such as MAPK and NF-κB. For skin brightening, it inhibits tyrosinase, the enzyme crucial for melanin production, which helps diminish dark spots and promote an even skin tone. Furthermore, it supports anti-aging by promoting collagen synthesis, enhancing skin elasticity, and boosting cellular vitality through mitophagy and ROS detoxification, contributing to cell renewal and improved skin resilience.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In vitro assays have demonstrated that Paeonia lactiflora flower extract exhibits significant antioxidant properties against DPPH, ABTS, and FRAP radicals, potent antiglycation capacity, and substantial inhibition of tyrosinase, cyclooxygenase-2, and collagenase.
  2. 02 Cellular experiments indicate that peony flower extract can inhibit nitric oxide and inflammatory factor release, decrease reactive oxygen species levels, prevent cell apoptosis, and inhibit the activation of MAPK and NF-κB signaling pathways, suggesting a therapeutic effect on skin inflammation.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 5 – 7
0 7 14

Stability

For optimal stability, a concentrated solution of peony flower extract is best diluted with water to achieve a pH of 6 ± 0.3 during preparation. Extremes, such as alkaline conditions or a pH around 3, can lead to the decomposition of its active substances, whereas a pH range of 5-7 supports stability.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) has not specifically assessed Paeonia Lactiflora Flower Extract. While a CIR review for *Paeonia suffruticosa*-derived ingredients noted insufficient data and did not include this specific extract, *Paeonia lactiflora root extract* has been deemed safe for cosmetic use up to a 1% concentration based on the Threshold of Toxicological Concern (TTC) approach. Generally, it is regarded as a safe ingredient in cosmetics with no widely known side effects or intolerances. However, individuals with known allergies to peonies or other related plants should exercise caution.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Paeonia Lactiflora Flower Extract is a valuable botanical offering comprehensive benefits for skin health, including antioxidant defense, anti-inflammatory action, and brightening effects, suitable for a wide array of precision skincare formulations.

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