Science
Mechanism of Action
This extract operates through several pathways to enhance skin health. Its richness in flavonoids and phenolic compounds confers robust antioxidant capabilities, actively neutralizing free radicals and shielding cellular structures from oxidative stress. Anti-inflammatory action is demonstrated by its ability to soothe irritation, diminish redness, and inhibit pro-inflammatory factors via deactivation of MAPK and NF-κB signaling. Glycosides within the extract serve as skin conditioning agents, promoting hydration and supporting optimal cellular function. Tannins contribute astringent properties, aiding in skin tightening and refining texture. Furthermore, it targets hyperpigmentation by inhibiting tyrosinase and reducing dark spots, while also offering anti-aging benefits through the inhibition of cyclooxygenase-2 and collagenase, supporting skin firmness.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 While specific clinical efficacy data for *Paeonia Lactiflora Bark/Sap Extract* is not extensively detailed at precise concentrations, a related *Paeonia lactiflora root extract* has a recommended usage level of 1-3% in formulations for complexion brightening, tone refinement, pore reduction, and anti-aging benefits. A safety assessment for *Paeonia lactiflora root extract* found it safe for cosmetic use at 1% concentration based on a Threshold of Toxicological Concern (TTC) approach.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The extract demonstrates stability within a pH range of approximately 5.05 to 7.0. For optimal preservation of its beneficial compounds, it is recommended to incorporate the extract during the cool-down phase of formulation, when temperatures are below 40°C (104°F).
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically evaluated *Paeonia Lactiflora Bark/Sap Extract*. However, a safety assessment for *Paeonia lactiflora root extract* using the Threshold of Toxicological Concern (TTC) approach determined it safe for cosmetic use at a 1% concentration. While some *Paeonia suffruticosa* extracts lacked sufficient data for safety determination, *Paeonia lactiflora root extract* and *Paeonia suffruticosa (Tree Peony) Root Bark Extract* were deemed safe. Generally, this extract is well-tolerated topically, with a low risk of irritation or sensitization as indicated by EWG's Skin Deep database, which assigns it a 'LOW' hazard rating for cancer, allergies, and developmental toxicity.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Paeonia Lactiflora Bark/Sap Extract is a valuable botanical offering diverse benefits, including antioxidant protection, anti-inflammatory action, hydration, and brightening, with a favorable safety profile across all skin types.
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