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Moumoujus

PABA SH-PENTAPEPTIDE-9.

Insufficient Data / BLEACHING, SKIN PROTECTING

PABA SH-PENTAPEPTIDE-9 is a sophisticated peptide complex, functioning as a cell-communicating ingredient to enhance skin vitality. It stimulates the formation of new blood vessels, delivering essential nutrients and oxygen for comprehensive skin renewal and structural reinforcement.

Summary

Cell-communicating ingredient Skin conditioning Promotes angiogenesis Enhances nutrient delivery to skin cells Supports fibroblast function Stimulates cell growth and migration Aids in wound healing Skin renewal Strengthens skin structure and barrier Revitalizes skin Anti-aging

Science

Mechanism of Action

This ingredient operates by leveraging the activity of SH-Polypeptide-9, an analog of Vascular Endothelial Growth Factor (VEGF). Its core mechanism is the stimulation of angiogenesis, promoting the formation of new capillaries. This process optimizes the delivery of nutrients and oxygen to dermal cells, which in turn supports fibroblast function, encourages cell proliferation and migration, and accelerates wound healing. These actions collectively contribute to revitalizing the skin, strengthening its intrinsic structure, and reinforcing the skin's natural barrier.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Conflicts

  • Should be avoided by individuals with psoriasis, sunburn, or those who have recently experienced high doses of UV radiation. The pro-angiogenic activity of SH-Polypeptide-9 (VEGFA) can exacerbate conditions like psoriasis and is not recommended for UV-damaged skin.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) has not specifically assessed PABA SH-PENTAPEPTIDE-9. However, the peptide component, SH-Polypeptide-9, is rated with low concern by EWG for cancer, allergies, immunotoxicity, and developmental/reproductive toxicity. PABA (para-aminobenzoic acid) is generally considered a non-toxic molecule. Despite low general concern, specific contraindications exist for individuals with certain skin conditions due to its mechanism of action.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

PABA SH-PENTAPEPTIDE-9 offers a compelling mechanism for skin renewal and strengthening via angiogenesis, with low reported irritancy, but specific clinical efficacy data and optimal usage concentrations are not detailed in the available research, warranting further investigation for precision application.

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