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Moumoujus

OZONIZED SACCHAROMYCES FERMENT LYSATE FILTRATE.

Valuable CAS - / SKIN CONDITIONING

This innovative ingredient is derived from Saccharomyces yeast, which undergoes a unique fermentation process involving a sublethal dose of ozone before cell lysis. The resulting filtrate is rich in key constituents that actively protect skin from environmental stressors. It demonstrably offers anti-aging benefits, significantly improves skin hydration, and reinforces the skin barrier.

Summary

skin conditioning antioxidant anti-aging moisturizing skin barrier support anti-inflammatory

Science

Mechanism of Action

Ozonized Saccharomyces Ferment Lysate Filtrate acts as a multifaceted cellular protector. It directly defends fragile cellular nucleic acids (both nuclear and mitochondrial DNA and RNA) and vital skin lipids against the damaging effects of ozone exposure. Furthermore, it actively prevents the formation of Advanced Glycation Endproducts (AGEs), which contribute to skin aging. Mechanistically, related ferment filtrates have been observed to promote Nrf2 nuclear translocation, upregulating key antioxidant proteins like NQO1 and HO-1, thereby mitigating reactive oxygen species (ROS) accumulation. It also modulates the c-Jun N-terminal kinase (JNK) pathway, reducing its activation in response to oxidative stress.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In vivo studies reveal its capacity to diminish wrinkles and enhance skin firmness.
  2. 02 It significantly reduces trans-epidermal water loss (TEWL) and boosts skin moisturization.
  3. 03 It actively targets and reduces Advanced Glycation Endproduct (AGE) formation.
  4. 04 It provides robust protection for fragile cellular nucleic acids (DNA and RNA) and skin lipids from the detrimental effects of ozone.
  5. 05 A related Saccharomyces/pearl ferment lysate filtrate has demonstrated efficacy in repairing UVB-induced skin barrier damage, restoring epidermal differentiation and tight junction proteins, reducing inflammatory markers, and alleviating common signs of sun damage such as peeling and erythema.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 4 – 5
0 7 14

Stability

Best performance is observed within an acidic pH range of 4.0-5.0, consistent with related Saccharomyces extracts.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically evaluated Ozonized Saccharomyces Ferment Lysate Filtrate. While related non-ozonized Saccharomyces ferment filtrates have shown safety in formulations up to 2%, with robust supporting data, GRAS status, and no toxicological alerts, this specific information is not directly applicable to the ozonized variant.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

This ingredient presents as a highly valuable active for comprehensive anti-aging and protective skincare, offering significant benefits against environmental damage and signs of aging, despite pending specific safety reviews for its ozonized form.

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