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OXO AZAANDROSTENE CARBOXYLOYL DECAPEPTIDE-18.

Valuable / SKIN CONDITIONING

OXO AZAANDROSTENE CARBOXYLOYL DECAPEPTIDE-18 is a signaling peptide engineered to activate the skin's intrinsic repair mechanisms. It is designed to stimulate regeneration in mature skin, reinforce its structural integrity, and visibly reduce the appearance of wrinkles, functioning as a sophisticated skin conditioning agent.

skin conditioning anti-aging reduces wrinkles improves elasticity skin regeneration strengthens skin structure

Science

This decapeptide operates by signaling to dermal cells, initiating the skin's inherent repair processes. It effectively boosts the often decelerated regenerative cycles of mature skin, fortifies its fundamental structure, and actively contributes to the visible amelioration of wrinkles.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 6 – 8
0 7 14

Stability

The stability and biological activity of this peptide are critically dependent on formulation conditions, including precise pH control (optimal between 6 and 8), temperature, and interactions with other ingredients. Chemical degradation by skin proteases represents a notable challenge to its sustained efficacy.

Conflicts

  • Strong Acids (e.g., AHAs, BHAs, L-Ascorbic Acid) can destabilize the peptide by shifting pH outside its optimal range.
  • Benzoyl Peroxide may induce oxidation, leading to deactivation.
  • Strong Retinoids, when co-applied, could potentially increase irritation; staggered application is advised.

Safety

CIR Status
Not reviewed
Sensitization risk Low

No specific safety assessment from CIR, SCCS, or FDA is available for OXO AZAANDROSTENE CARBOXYLOYL DECAPEPTIDE-18. However, peptides in general are typically considered well-tolerated in cosmetic applications.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

This peptide holds promise for mature skin by signaling repair and regeneration; however, specific clinical efficacy data for this exact ingredient is currently limited, warranting careful formulation and continued research.


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