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Moumoujus

OXACYCLOHEXADECENONE.

Optional CAS 34902-57-3 / FRAGRANCE, PERFUMING

Oxacyclohexadecenone is a fragrance ingredient known for imparting a soft, metallic-powdery musk aroma. Its primary function in skincare is to enhance the sensory experience of a product by perfuming the skin or masking undesirable base odors, providing excellent tenacity.

Summary

perfuming masking

Science

Mechanism of Action

This ingredient functions by volatilizing from the product matrix to interact with olfactory receptors, delivering a distinct musk scent profile described as soft and metallic-powdery. It also serves to reduce or inhibit the perception of basic odors or tastes inherent to a product's formulation, thereby improving overall user experience.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

No data available indicates this ingredient is commonly associated with dusting issues in formulations.

The Formula

Formulation

Solubility
Oil
Optimal pH 2 – 10
0 7 14

Stability

Oxacyclohexadecenone exhibits robust stability across a wide pH spectrum, specifically from 2.0 to 10.0. It maintains integrity in diverse systems, including alcohol-based formulations, body lotions, emulsion systems, citric acid cleaners, and alkaline solutions. Good stability is also noted with shampoos, soaps, and concentrated detergent powders.

Conflicts

  • bleach

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The Research Institute for Fragrance Materials (RIFM) has concluded that Oxacyclohexadecenone is safe for use as described in their peer-reviewed assessment. RIFM has established a maximum acceptable concentration level across various product categories, including cosmetics and personal care, to mitigate skin sensitization risk. It is not genotoxic, phototoxic, or photoallergenic. The No Expected Sensitization Induction Level (NESIL) is 7500 μg/cm2, indicating a low potential for sensitization at typical usage levels. A Margin of Exposure (MOE) greater than 100 has been observed for repeated dose and reproductive toxicity endpoints. While safe for human use at determined levels, GHS classification indicates it is very toxic to aquatic life with long-lasting effects.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Optional

Oxacyclohexadecenone is an optional ingredient, primarily valued for its precise soft, metallic-powdery musk fragrance and odor-masking capabilities, contributing to the sensory elegance of a formulation rather than direct skin health benefits.

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