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Moumoujus

OSTREA EDULIS EXTRACT.

Insufficient Data CAS 94465-79-9 / SKIN CONDITIONING

Ostrea Edulis Extract, derived from the European flat oyster, is a marine ingredient celebrated for its rich composition of essential minerals, amino acids, and antioxidants. It aims to support skin regeneration, enhance overall skin texture, and provide protection against environmental stressors. This extract promotes a more resilient and balanced complexion.

Summary

Antioxidant Anti-inflammatory Skin Conditioning Oil Regulating Anti-aging Skin Regeneration

Science

Mechanism of Action

This extract delivers a concentrated array of vital nutrients that support skin health. Its mineral and amino acid content aids cellular regeneration and metabolic activity, while inherent antioxidants combat oxidative stress by reducing reactive oxygen species and boosting endogenous antioxidant enzymes like SOD and GSH-px. It is also understood to regulate sebum production and exhibit anti-inflammatory properties by inhibiting key inflammatory markers such as IL-1β, IL-6, TNF-α, iNOS, COX-2, and NF-κB, alongside purportedly promoting collagen synthesis to maintain skin elasticity.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Topical application of peptides derived from *Crassostrea hongkongensis* (a distinct oyster species) in mice demonstrated significant amelioration of UVB-induced skin photodamage. Benefits observed included reduced moisture loss, diminished epidermal hyperplasia, preservation of collagen and elastin fibers, enhanced antioxidant enzyme activity (SOD, GPH-Px), decreased malondialdehyde (MDA) levels, and a reduction in inflammatory cytokines (IL-1β, IL-6, TNF-α) and inflammation-related protein expression (iNOS, COX-2, MMP1).
  2. 02 In vitro studies on human dermal fibroblasts using shell extracts from *Mytilus edulis* (mussel) and *Crassostrea gigas* (Pacific oyster, another distinct species) showed stimulated metabolic activity and cell proliferation. However, these extracts also led to a decrease in type I collagen and a concurrent increase in active MMP-1, indicating a promotion of the catabolic pathway within fibroblasts.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

While no specific optimal pH range for the stability of Ostrea Edulis Extract in cosmetic formulations has been identified, marine ingredients are generally recognized for their resilience across varying pH and temperature conditions.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) has not published a specific safety assessment for Ostrea Edulis Extract. While Ostrea edulis shell extract is found in some OTC products, it is not an approved drug by the FDA. Individuals with known seafood allergies are advised to exercise caution.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

Ostrea Edulis Extract presents a theoretically beneficial profile due to its rich nutrient content and described mechanisms, but robust direct clinical evidence specific to this extract and its full range of claimed benefits, particularly collagen synthesis, is currently limited and requires further investigation.

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