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Moumoujus

ORYZA SATIVA CALLUS EXTRACT.

Essential / SKIN CONDITIONING

Oryza Sativa Callus Extract, derived from rice stem cells, is a multi-functional botanical powerhouse. It delivers significant skin brightening by inhibiting melanin, provides robust antioxidant protection, and enhances skin hydration and elasticity, making it ideal for comprehensive skin revitalization.

Summary

skin conditioning antioxidant moisturizing skin protecting smoothing soothing

Science

Mechanism of Action

This extract's efficacy stems from its rich concentration of polyphenols and flavonoids, which exert powerful antioxidant activity. These compounds effectively neutralize free radicals and mitigate UV-induced oxidative damage, directly contributing to reduced hyperpigmentation and prevention of premature aging. As a potent skin conditioning agent, it provides a wealth of amino acids that significantly boost hydration, enhance moisture retention, and smooth skin texture. Furthermore, its anti-inflammatory properties offer a calming effect on irritated skin, while promoting vital cell growth, rejuvenation, and keratinocyte migration crucial for skin repair and wound healing.

Research

Clinical Evidence

High confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 85% inhibition of melanin biosynthesis with an aqueous extract at 3200 µg/mL, demonstrating 1.7 times greater effectiveness than arbutin in addressing hyperpigmentation.
  2. 02 Significantly enhanced antioxidant activity, comparable to arbutin at 100 mg/mL, with an IC50 of 42.24 ± 0.67 mg/mL for ABTS radical scavenging.
  3. 03 Proven to reduce melanin content and elevate skin moisture and elasticity, particularly beneficial for aging skin.
  4. 04 Enhanced skin keratinocyte migration at 50 µg/mL (crude ethanol extract), increasing gene expressions for critical cell migration-related growth factors (PDGF-B, TGF-β1, HB-EGF, FGF-2) essential for wound healing.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 4.5 – 7
0 7 14

Stability

The stated pH range is for general Oryza Sativa Extract, suggesting applicability.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While the Cosmetic Ingredient Review (CIR) has not specifically assessed Oryza Sativa Callus Extract, other Oryza Sativa derivatives have been deemed safe for cosmetic use. COSMILE Europe classifies this extract as a skin conditioning agent without any noted penalties. Cosmetic ingredients are not typically pre-approved by the FDA unless classified as drugs.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Essential

Oryza Sativa Callus Extract is an essential active, offering clinically demonstrated brightening and antioxidant capabilities, coupled with significant moisturizing and regenerative benefits, making it highly versatile for all skin types.

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