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Moumoujus

OROSTACHYS JAPONICA/SAURURUS CHINENSIS EXTRACT.

Valuable / HUMECTANT, SKIN CONDITIONING

This botanical extract, a blend of Orostachys japonica and Saururus chinensis, acts as a multi-functional agent, providing humectant and skin conditioning properties. It is scientifically recognized for its diverse potential, including antioxidant, anti-inflammatory, and specific anti-aging benefits, supporting overall skin health and resilience.

Summary

Humectant Skin Conditioning Antimicrobial Antioxidant Astringent Emollient Skin Protecting

Science

Mechanism of Action

The extract functions primarily as a humectant and skin conditioning agent. Orostachys japonica contributes antioxidant, anti-inflammatory, and anti-wrinkle benefits through inhibition of enzymes like elastase, collagenase, MMP-1, and MMP-3. It also exhibits tyrosinase-inhibiting (whitening) and immunostimulatory activities, and can mitigate atopic dermatitis-like symptoms by reducing TARC expression and suppressing NF-κB and STAT1 activation. Saururus chinensis complements these effects with antimicrobial, antioxidant, astringent, emollient, and skin-protecting qualities, alongside its own anti-inflammatory actions.

Research

Clinical Evidence

Medium confidence
Effective range 0.05–3%
Optimal

2%

Key findings

  1. 01 Ethanol extracts of Orostachys japonica leaf demonstrated minimum inhibitory concentrations (MIC) against gram-positive bacteria and yeast, highlighting its potential antimicrobial properties.
  2. 02 Orostachys japonica extract is suggested for topical skin applications in creams and ointments, indicating a potential effective concentration range for general cosmetic use.
  3. 03 Orostachys japonica extracts exhibited minimum cytotoxicity in human skin fibroblast (HS68) and mouse melanoma (B16F10) cells, suggesting a favorable safety profile at these concentrations.
  4. 04 Orostachys japonica ethanol extract (OJEE) reduced atopic dermatitis-like skin lesions in NC/Nga mice and suppressed TNF-α/IFN-γ-increased TARC mRNA levels in HaCaT cells, suggesting significant anti-inflammatory effects on skin.
  5. 05 Treatment with Saururus chinensis water extract decreased serum levels of pro-inflammatory cytokines (Interleukin-6, TNF-alpha) and reduced swelling in an animal model of arthritis, indicating systemic anti-inflammatory potential.

Transparency

Dusting Analysis

Not commonly dusted

The provided research does not offer information regarding common dusting practices or specific concentration thresholds for this extract combination.

The Formula

Formulation

Solubility
Water
Optimal pH 2 – 10
0 7 14

Stability

Ethanol extracts of Orostachys japonica leaf demonstrate antimicrobial and antioxidant activities that are stable under heat and show broad pH tolerance, with efficacy maintained across a pH range of 2 to 10.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) has not specifically evaluated 'OROSTACHYS JAPONICA/SAURURUS CHINENSIS EXTRACT'. No specific safety data for Saururus Chinensis Leaf/Root Extract is available on SpecialChem, and Paula's Choice lists the ingredient as 'Not rated' with 'No known benefits'. There is no specific FDA status or SCCS opinion for this combined extract.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

With a broad spectrum of potential benefits including antioxidant defense, anti-inflammatory action, and skin conditioning, this extract shows promise across all skin types, though comprehensive human topical safety and efficacy data for the combined ingredient are still developing.

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