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Moumoujus

OPUNTIA HUMIFUSA FLOWER/STEM EXTRACT.

Valuable / ASTRINGENT, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING

Opuntia Humifusa Flower/Stem Extract is a multi-functional botanical offering significant protection against environmental stressors like UV radiation and particulate matter. It actively enhances skin hydration by regulating hyaluronic acid production and supports collagen synthesis, promoting overall skin health and resilience.

Summary

Astringent Hair conditioning Humectant Skin conditioning Antioxidant Anti-inflammatory Photo-protective Hydration regulation Collagen synthesis support Pollution protection Melanin inhibition

Science

Mechanism of Action

This extract leverages potent antioxidant and anti-inflammatory properties to modulate inflammatory cytokine expression, thereby reducing skin damage. It critically regulates hyaluronic acid (HA) homeostasis by significantly increasing HA synthases (HAS) mRNA levels while decreasing UVB-induced hyaluronidase mRNA. Rich in polyphenols, polyunsaturated fatty acids, and amino acids, it provides essential replenishing and hydrating benefits. Furthermore, the presence of piscidic acid, an iron chelator, helps prevent free radical formation and neutralizes the damaging effects of airborne pollutants, supporting collagen synthesis and potentially inhibiting melanin production.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In UVB-irradiated HaCaT cells, a 100 μg/mL concentration boosted HA synthases (HAS1, HAS2, HAS3) mRNA levels by 1.9-, 2.2-, and 1.6-fold respectively. Concurrently, it decreased UVB-induced hyaluronidase mRNA by 35%. In hairless mice, it decreased HA content from 42.9 to 27.1 ng/mL, reduced epidermal thickness by 45% (from 45.7 to 24.2 μm), lowered transepidermal water loss (TEWL) by 48% (from 48.8 to 25 g/h/m2), and diminished erythema by 33%. These effects collectively indicate protection against UVB-induced skin degeneration.
  2. 02 Demonstrated prevention of particulate matter-induced skin oxidative stress and inflammation, alongside an enhancement of collagen synthesis.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

EWG Skin Deep assigns 'LOW' hazard scores across critical categories including Cancer, Allergies & Immunotoxicity, and Developmental and Reproductive Toxicity, indicating a favorable safety profile. Research also confirms its non-toxicity to normal human cells.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Opuntia Humifusa Flower/Stem Extract is a valuable multi-tasking ingredient, effectively protecting skin from environmental damage, boosting hydration, and supporting anti-aging mechanisms with a strong safety profile.

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