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Moumoujus

OPOPONAX OIL.

Avoid CAS 8021-36-1 / 100084-96-6 / FRAGRANCE

Opoponax oil, derived from the resin of the Commiphora tree, is an aromatic compound recognized for its traditional use in supporting skin health. While it possesses reported antiseptic and anti-inflammatory properties, its application in precision skincare requires careful consideration due to its notable safety profile.

Summary

fragrance antiseptic anti-inflammatory astringent antioxidant antimicrobial

Science

Mechanism of Action

Opoponax oil's biological activity is attributed to its complex chemical composition, which includes phenolics, diterpenes, coumarins, and phthalides. These compounds are believed to confer antioxidant and antimicrobial actions. In topical applications, the oil is traditionally associated with antiseptic and anti-inflammatory effects, contributing to the management of minor skin irritations and possessing astringent qualities that may promote skin rejuvenation.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Recommended as a dermal maximum usage level due to moderate risk of skin sensitization and phototoxicity by Tisserand and Young.
  2. 02 IFRA standard recommends this maximum level in consumer products, based on industry test results, due to sensitization risk.
  3. 03 In closed patch tests, 2 out of 65 dermatitis patients exhibited reactions when exposed to Opoponax oil at 5% in petrolatum.

Transparency

Dusting Analysis

Not commonly dusted

No available data suggests Opoponax oil is commonly subject to 'dusting' or exaggerated marketing claims without scientific substantiation regarding specific efficacy thresholds.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Opoponax oil exhibits good stability under standard storage conditions. For optimal shelf life, it should be kept in an airtight container at ambient temperature, in dry conditions, and away from light. Extreme heat should be avoided.

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
0.6%
Sensitization risk Moderate

Opoponax oil is phototoxic and presents a moderate risk of skin sensitization, potentially leading to irritation or allergic reactions. Its topical application is strongly discouraged for individuals with hypersensitive, diseased, or damaged skin. The SCCP acknowledged its allergenic potential but considered the risk low at a maximum concentration of 0.6% in finished cosmetic products. It holds FDA GRAS status for food flavoring, which does not extend to specific cosmetic approval.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Opoponax oil carries a notable risk of sensitization and phototoxicity, limiting its safe dermal usage to a maximum of 0.6%, with traditional benefits not clinically substantiated for efficacy in precision skincare.

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