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Moumoujus

OPOPANAX CHIRONIUM RESIN EXTRACT.

Avoid CAS 93384-32-8 / PERFUMING

OPOPANAX CHIRONIUM RESIN EXTRACT is derived from the natural resin of the *Opopanax chironium* plant, a botanical historically valued for its aromatic properties. Its complex composition includes phenolics, diterpenes, coumarins, and phthalides. These compounds collectively contribute to its reported antioxidant, antimicrobial, and anti-inflammatory activities.

Summary

perfuming antioxidant anti-inflammatory antimicrobial

Science

Mechanism of Action

The extract functions through its rich profile of bioactive compounds. Phenolics and diterpenes likely exert antioxidant effects by neutralizing free radicals, thereby protecting skin from oxidative stress. Its anti-inflammatory properties, potentially mediated by coumarins and phthalides, aim to reduce inflammatory pathways, offering a soothing effect on irritated skin. Additionally, it exhibits a reported antimicrobial action.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Stability

When Opopanax oil is obtained through pyrolysis, it is crucial that the product undergoes rectification. This process is necessary to ensure that the content of Polycyclic Aromatic Hydrocarbons (PAH), specifically Benzopyrene and 1,2-Benzanthracene, does not exceed 1 ppb in the final formulation.

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
0.46%
Sensitization risk High

The Cosmetic Ingredient Review (CIR) Expert Panel has not formally assessed OPOPANAX CHIRONIUM RESIN EXTRACT. It is important to note that the SCCS opinion for 'Opoponax' pertains to *Commiphora erythraea var. glabrescens*, a distinct botanical source. While the FDA lists 'OPOPANAX TINCTURE' as a flavoring agent, the International Fragrance Association (IFRA) identifies dermal sensitization as a critical concern for this extract. IFRA standards restrict its use, permitting a maximum concentration of 0.46% in products applied to the face/body using fingertips (Category 3). Stringent processing to limit PAH content to below 1 ppb is also mandated.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Despite mechanistic evidence suggesting antioxidant, anti-inflammatory, and antimicrobial properties, the absence of clinical studies demonstrating efficacy, coupled with a high risk of dermal sensitization and strict regulatory requirements for Polycyclic Aromatic Hydrocarbon (PAH) content, renders OPOPANAX CHIRONIUM RESIN EXTRACT unsuitable for precision skincare formulations.

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