Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

OPHIOPOGON JAPONICUS SEED EXTRACT.

Valuable CAS 952500-62-8 / SKIN PROTECTING

This botanical extract, derived from the seeds of Ophiopogon japonicus, is a multifaceted ingredient renowned for its exceptional ability to fortify the skin's natural barrier. Rich in beneficial compounds like fructans, it significantly enhances skin hydration, reduces inflammation, and offers antioxidant protection, making it particularly beneficial for sensitive and compromised skin.

Summary

skin protecting moisturizer anti-inflammatory antioxidant barrier strengthening soothing

Science

Mechanism of Action

Ophiopogon Japonicus Seed Extract acts through several pathways. It profoundly moisturizes by preventing transepidermal water loss (TEWL) and stimulating the synthesis of crucial tight junction proteins (claudin-1, ZO-1), while also increasing filaggrin levels and promoting urea production for a robust skin barrier. Its anti-inflammatory properties stem from inhibiting leukocyte migration, reducing NF-κB activation, lowering pro-inflammatory cytokines (IL-8, TNF-α), and deactivating the itch receptor TRPA1. Furthermore, its flavonoid content provides antioxidant benefits by neutralizing reactive oxygen species.

Research

Clinical Evidence

High confidence
Effective range 0.05–5%
Optimal

N/A

Key findings

  1. 01 Clinical trials demonstrated significant efficacy in treating atopic dermatitis, reducing relapse rates, severity, intensity, and frequency of flare-ups, thereby improving patients' quality of life. Oligofructans from the extract notably reduced SCORAD scores (erythema, pruritus, body surface area) in both children and adults with mild-to-moderate atopic dermatitis, with effective concentrations reported between 0.05% and 1%.
  2. 02 The extract visibly strengthens the skin's barrier by boosting urea levels in the surface layers, which effectively prevents water loss and maintains adequate hydration. This barrier-strengthening effect has been observed at concentrations ranging from 1% to 5% (often in a blend).

Transparency

Dusting Analysis

Not commonly dusted

No data available in the provided research suggests that Ophiopogon Japonicus Seed Extract is commonly used in 'dusting' concentrations (negligible amounts primarily for marketing claims).

The Formula

Formulation

Solubility
Water
Optimal pH 4.5 – 6.5
0 7 14

Stability

Optimal stability for Ophiopogon japonicus extract is observed within a pH range of 4.5 to 6.5.

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
5%
Sensitization risk Low

Ophiopogon Japonicus Seed Extract is generally regarded as safe for cosmetic use when applied as directed. It has been shown to be non-irritating and non-sensitizing at concentrations up to 5% in leave-on products for adults and infants. However, individuals with known allergies or highly sensitive skin should perform a patch test. Data regarding its topical safety during pregnancy and breastfeeding are currently lacking, so consultation with a healthcare professional is advised.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Ophiopogon Japonicus Seed Extract is a valuable botanical ingredient, clinically shown to strengthen the skin barrier, provide significant hydration, soothe inflammation, and protect against oxidative stress, making it highly beneficial for sensitive and compromised skin types across a dosage range of 0.05% to 5%.

Related

Similar Ingredients

Finding similar ingredients…