Science
Mechanism of Action
The efficacy of Ophiopogon Extract Stearate, primarily attributable to its active Ophiopogon Japonicus Root Extract components, operates through several key pathways. It exhibits potent anti-inflammatory effects by reducing nuclear translocation of NF-κB and inhibiting pro-inflammatory cytokines such as IL-8 and TNF-α, mediated by homoisoflavonoids and ophiopogonin D. For soothing, it deactivates the TRPA1 itch receptor, effectively mitigating irritation and redness. Its robust moisturizing action is driven by hygroscopic polysaccharides (fructo-oligose, fructosan) that retain moisture, complemented by enhanced skin barrier function through increased synthesis of tight junction proteins (claudin-1, ZO-1) and filaggrin. Furthermore, it offers antioxidant protection against oxidative stress with its rich content of homoisoflavonoids and flavonoids, gently contributes to an even skin tone by inhibiting tyrosinase, and supports anti-aging by promoting fibroblast proliferation for improved elasticity and firmness.
Research
Clinical Evidence
High confidence3%
Key findings
- 01 Recommended for general moisturizing products at 3.0-5.0%.
- 02 Recommended for high moisturizing, soothing, or barrier repair formulations at 5.0-10.0%.
- 03 Usage levels as a blend with butylene glycol observed at 1-5% in skincare products.
- 04 Recommended general dosage for Ophiopogon japonicus plant extract in formulations is 0.05-1%.
Transparency
Dusting Analysis
The recommended effective concentrations for Ophiopogon Japonicus Root Extract, ranging from 0.05% to 10.0% depending on the desired benefit, indicate that this ingredient is intended for functional inclusion rather than minimal 'dusting' for marketing purposes.
The Formula
Formulation
Stability
The optimal pH range for the stability of Ophiopogon japonicus extract is precisely between 5.0 and 6.0. The primary active components, such as polysaccharides, are soluble in water and ethanol. While the extract itself is water-soluble, the 'stearate' modification in 'Ophiopogon Extract Stearate' typically imparts oil solubility, suggesting the complex may have unique dispersion properties, though specific data for this exact compound's solubility is not available.
Safety
Safety Profile
Information specifically for 'OPHIOPOGON EXTRACT STEARATE' regarding CIR, SCCS, or FDA status is not directly available, and it is not an INCI-standard name. However, the underlying Ophiopogon Japonicus Root Extract is generally well-tolerated, with rare instances of mild irritation reported only for very sensitive skin. No public official safety assessment or maximum concentration for cosmetic use from CIR or SCCS is provided for the root extract.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Ophiopogon Extract Stearate, leveraging the benefits of Ophiopogon Japonicus Root Extract, is a valuable ingredient for advanced skincare formulations, offering significant hydration, barrier repair, and soothing properties with low irritancy and comedogenicity, despite specific safety review data for the stearate compound being unavailable.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources