Science
Mechanism of Action
This ingredient's primary function is as a hair conditioning agent. Regarding its specific mechanism of action on the skin, comprehensive data for OLIGOPEPTIDE-91 SH-POLYPEPTIDE-2 is not readily available. However, the SH-POLYPEPTIDE-2 component within this ingredient, often identified as Insulin-like Growth Factor-1 (IGF-1), is understood to stimulate the production of collagen, promote cellular proliferation and aid in tissue repair, enhance skin elasticity, and increase the synthesis of hyaluronic acid.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
General peptide stability is influenced by pH, with potential hydrolysis at acidic (pH 1-3) or slightly acidic (pH 5-6) conditions and epimerization occurring at alkaline (pH > 7) conditions. Specific stability data for OLIGOPEPTIDE-91 SH-POLYPEPTIDE-2 is not provided.
Safety
Safety Profile
While SH-Oligopeptide-2 is generally considered safe by some regulatory authorities, with no reported serious side effects, growth factors and their mimics, including IGF-1 (SH-Oligopeptide-2), are advised to be used with caution. Potential correlations with tumorigenesis or disease progression have been noted, and concerns exist regarding the unknown long-term risks of similar peptides in cosmetic applications.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While recognized for hair conditioning and its SH-POLYPEPTIDE-2 component shows promising skin benefits related to anti-aging, specific skin efficacy data for OLIGOPEPTIDE-91 SH-POLYPEPTIDE-2 is lacking, and its growth factor component warrants significant caution due to potential long-term safety concerns.
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